Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial.

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第一作者： Jean-Claude,Tardif

第一单位： Montreal Heart Institute, Université de Montréal, Montreal, QC, Canada. Electronic address: jean-claude.tardif@icm-mhi.org.

作者： Jean-Claude,Tardif ^[1] ; Nadia,Bouabdallaoui ^[2] ; Philippe L,L'Allier ^[2] ; Daniel,Gaudet ^[3] ; Binita,Shah ^[4] ; Michael H,Pillinger ^[4] ; Jose,Lopez-Sendon ^[5] ; Protasio,da Luz ^[6] ; Lucie,Verret ^[2] ; Sylvia,Audet ^[2] ; Jocelyn,Dupuis ^[2] ; André,Denault ^[2] ; Martin,Pelletier ^[7] ; Philippe A,Tessier ^[7] ; Sarah,Samson ^[2] ; Denis,Fortin ^[2] ; Jean-Daniel,Tardif ^[2] ; David,Busseuil ^[2] ; Elisabeth,Goulet ^[2] ; Chantal,Lacoste ^[2] ; Anick,Dubois ^[2] ; Avni Y,Joshi ^[8] ; David D,Waters ^[9] ; Priscilla,Hsue ^[9] ; Norman E,Lepor ^[10] ; Frédéric,Lesage ^[2] ; Nicolas,Sainturet ^[11] ; Eve,Roy-Clavel ^[11] ; Zohar,Bassevitch ^[11] ; Andreas,Orfanos ^[11] ; Gabriela,Stamatescu ^[11] ; Jean C,Grégoire ^[2] ; Lambert,Busque ^[12] ; Christian,Lavallée ^[12] ; Pierre-Olivier,Hétu ^[13] ; Jean-Sébastien,Paquette ^[14] ; Spyridon G,Deftereos ^[15] ; Sylvie,Levesque ^[11] ; Mariève,Cossette ^[11] ; Anna,Nozza ^[11] ; Malorie,Chabot-Blanchet ^[11] ; Marie-Pierre,Dubé ^[2] ; Marie-Claude,Guertin ^[11] ; Guy,Boivin ^[7] ; COLCORONA Investigators

作者单位： Montreal Heart Institute, Université de Montréal, Montreal, QC, Canada. Electronic address: jean-claude.tardif@icm-mhi.org. ^[1] Montreal Heart Institute, Université de Montréal, Montreal, QC, Canada. ^[2] Ecogene-21, Université de Montréal, Montreal, QC, Canada; Department of Medicine, Université de Montréal, Montreal, QC, Canada. ^[3] New York University Grossman School of Medicine, New York, NY, USA. ^[4] H La Paz, IdiPaz, UAM, Ciber-CV, Madrid, Spain. ^[5] Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brasil. ^[6] Centre Hospitalier Universitaire de Québec, Université Laval, Quebec City, QC, Canada. ^[7] Mayo Clinic, Rochester, MN, USA. ^[8] San Francisco General Hospital, San Francisco, CA, USA. ^[9] Cedars-Sinai Heart Institute, Geffen School of Medicine-UCLA, Los Angeles, CA, USA. ^[10] Montréal Health Innovations Coordinating Center, Montreal, QC, Canada. ^[11] Hôpital Maisonneuve-Rosemont, Université de Montréal, Montreal, QC, Canada. ^[12] Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada. ^[13] Université Laval, Quebec City, QC, Canada. ^[14] Second Department of Cardiology, National and Kapodistrian University of Athens, Athens, Greece. ^[15]

主题词投药, 口服(Administration, Oral);门诊医疗(Ambulatory Care);消炎药(Anti-Inflammatory Agents);秋水仙碱(Colchicine);双盲法(Double-Blind Method);药物监测(Drug Monitoring);女(雌)性(Female);住院(Hospitalization);人类(Humans);意向治疗分析(Intention to Treat Analysis);男(雄)性(Male);中年人(Middle Aged);危险性评估(Risk Assessment)

DOI 10.1016/S2213-2600(21)00222-8

PMID 34051877

发布时间 2022-12-07

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The Lancet. Respiratory medicine

2021年9卷8期

924-932页

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Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial.

The Lancet. Respiratory medicine

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Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial.

The Lancet. Respiratory medicine

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The Lancet. Respiratory medicine

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