Effect of age on brain metabotropic glutamate receptor subtype 5 measured with [<sup>18</sup>F]FPEB PET.

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第一作者： Adam P,Mecca

第一单位： Alzheimer's Disease Research Unit, Yale University School of Medicine, One Church Street, 8th Floor, New Haven, CT, 06514, USA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. Electronic address: adam.mecca@yale.edu.

作者： Adam P,Mecca ^[1] ; Kelly,Rogers ^[2] ; Zachary,Jacobs ^[2] ; Julia W,McDonald ^[2] ; Hannah R,Michalak ^[2] ; Nicole,DellaGioia ^[3] ; Wenzhen,Zhao ^[2] ; Ansel T,Hillmer ^[4] ; Nabeel,Nabulsi ^[5] ; Keunpoong,Lim ^[5] ; Jim,Ropchan ^[5] ; Yiyun,Huang ^[5] ; David,Matuskey ^[6] ; Irina,Esterlis ^[3] ; Richard E,Carson ^[5] ; Christopher H,van Dyck ^[7]

作者单位： Alzheimer's Disease Research Unit, Yale University School of Medicine, One Church Street, 8th Floor, New Haven, CT, 06514, USA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. Electronic address: adam.mecca@yale.edu. ^[1] Alzheimer's Disease Research Unit, Yale University School of Medicine, One Church Street, 8th Floor, New Haven, CT, 06514, USA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. ^[2] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. ^[3] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA. ^[4] Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA. ^[5] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA; Department of Neurology, Yale University School of Medicine, New Haven, CT, USA. ^[6] Alzheimer's Disease Research Unit, Yale University School of Medicine, One Church Street, 8th Floor, New Haven, CT, 06514, USA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; Department of Neuroscience, Yale University School of Medicine, New Haven, CT, USA; Department of Neurology, Yale University School of Medicine, New Haven, CT, USA. ^[7]

关键词 Aging Glutamate receptor [(18)F]FPEB, PET mGluR5

主题词青少年(Adolescent);成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);衰老(Aging);脑化学(Brain Chemistry);女(雌)性(Female);氟放射性同位素(Fluorine Radioisotopes);氟脱氧葡萄糖F18(Fluorodeoxyglucose F18);海马(Hippocampus);人类(Humans);磁共振成像(Magnetic Resonance Imaging);男(雄)性(Male);中年人(Middle Aged);器官测量(Organ Size);正电子发射断层显像术(Positron-Emission Tomography);放射性药物(Radiopharmaceuticals);青年人(Young Adult)

DOI 10.1016/j.neuroimage.2021.118217

PMID 34052464

发布时间 2024-09-23

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Effect of age on brain metabotropic glutamate receptor subtype 5 measured with [<sup>18</sup>F]FPEB PET.

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Effect of age on brain metabotropic glutamate receptor subtype 5 measured with [<sup>18</sup>F]FPEB PET.

NeuroImage

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NeuroImage

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