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Intrathecal Immunoglobulin M Synthesis is an Independent Biomarker for Higher Disease Activity and Severity in Multiple Sclerosis.

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第一作者: Johanna,Oechtering
第一单位: Neurology Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.
作者单位: Neurology Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland. [1] Clinical Trial Unit, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland. [2] Department of Neurology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland. [3] Department of Neurology, Cantonal Hospital Aarau, Aarau, Switzerland. [4] Neurocentre of Southern Switzerland, Multiple Sclerosis Centre, Ospedale Civico, Lugano, Switzerland. [5] Department of Neurology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland. [6] Division of Neurology, Department of Clinical Neurosciences, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland. [7] Neurology Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.;Translational Imaging in Neurology (ThINk) Basel, Department of Biomedical Engineering, Faculty of Medicine, University Hospital Basel and University of Basel, Basel, Switzerland. [8] Division of Medical Immunology, Laboratory Medicine, University Hospital Basel, Basel, Switzerland. [9] Department of Clinical Neurosciences, Division of Neurology, Geneva University Hospital, Geneva, Switzerland.;Diagnostic Department, Division of Laboratory Medicine, Geneva University Hospital, Geneva, Switzerland.;Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland. [10] Medical Image Analysis Center (MIAC) and Department of Biomedical Engineering, University Basel, Basel, Switzerland. [11] Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland. [12] Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada. [13] Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany. [14] Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany. [15] Division of Neuroradiology, Department of Radiology and Nuclear Medicine, University Hospital Basel, University of Basel, Basel, Switzerland. [16] Neurology Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.;Medical Image Analysis Center (MIAC) and Department of Biomedical Engineering, University Basel, Basel, Switzerland. [17] Medica Laboratory, Zürich, Switzerland. [18] Neurocentre of Southern Switzerland, Multiple Sclerosis Centre, Ospedale Civico, Lugano, Switzerland.;Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland. [19] Neurology Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.;Neurocentre of Southern Switzerland, Multiple Sclerosis Centre, Ospedale Civico, Lugano, Switzerland.;Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland. [20]
DOI 10.1002/ana.26137
PMID 34057235
发布时间 2021-11-08
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Annals of neurology

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