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首页> Reproductive biology> Thrombin impairs the angiogenic activity of extravillous trophoblast cells via monocyte chemotactic protein-1 (MCP-1): A possible link with preeclampsia.

Thrombin impairs the angiogenic activity of extravillous trophoblast cells via monocyte chemotactic protein-1 (MCP-1): A possible link with preeclampsia.

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作者： Daniela,Brünnert ^[1] ; Vijay,Kumar ^[2] ; Vibha,Kaushik ^[2] ; Jens,Ehrhardt ^[3] ; Kirti Raj,Chahar ^[2] ; Phulwanti Kumari,Sharma ^[2] ; Marek,Zygmunt ^[3] ; Pankaj,Goyal ^[4]

作者单位： Experimental Tumor Immunology, Department of Obstetrics and Gynecology, University of Würzburg Medical School, D-97080, Würzburg, Germany; Department of Obstetrics and Gynecology, University of Greifswald, Ferdinand-Sauerbruchstrasse, D-17489, Greifswald, Germany. Electronic address: Bruennert_d@ukw.de. ^[1] Department of Biotechnology, School of Life Sciences, Central University of Rajasthan, Bandarsindri, Kishangarh, Rajasthan, 305817, India. ^[2] Department of Obstetrics and Gynecology, University of Greifswald, Ferdinand-Sauerbruchstrasse, D-17489, Greifswald, Germany. ^[3] Department of Biotechnology, School of Life Sciences, Central University of Rajasthan, Bandarsindri, Kishangarh, Rajasthan, 305817, India. Electronic address: pankaj_bio@curaj.ac.in. ^[4]

关键词 Monocyte chemotactic protein1 (MCP-1)PKC Preeclampsia Rho kinase Thrombin Trophoblast

主题词细胞系(Cell Line);趋化因子CCL2(Chemokine CCL2);女(雌)性(Female);基因表达调控(Gene Expression Regulation);人类(Humans);新生血管化, 生理性(Neovascularization, Physiologic);先兆子痫(Pre-Eclampsia);妊娠(Pregnancy);蛋白激酶Cα(Protein Kinase C-alpha);受体, PAR-1(Receptor, PAR-1);凝血酶(Thrombin);rho相关激酶类(rho-Associated Kinases)

DOI 10.1016/j.repbio.2021.100516

PMID 34058707

发布时间 2022-01-26

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Reproductive biology

Reproductive biology

2021年21卷3期

100516页

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