miR-506-loaded gelatin nanospheres target PENK and inactivate the ERK/Fos signaling pathway to suppress triple-negative breast cancer aggressiveness.
第一作者:
Xin-Li,Liu
第一单位:
Institute for Special Environmental Biophysics, Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China.
作者:
主题词
动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);疾病模型, 动物(Disease Models, Animal);疾病恶化(Disease Progression);脑啡肽类(Enkephalins);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);女(雌)性(Female);明胶(Gelatin);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因转移技术(Gene Transfer Techniques);人类(Humans);小鼠(Mice);微RNAs(MicroRNAs);纳米球(Nanospheres);蛋白质前体(Protein Precursors);原癌基因蛋白质c-fos(Proto-Oncogene Proteins c-fos);信号传导(Signal Transduction);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1002/mc.23310
PMID
34062009
发布时间
2021-09-27
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Molecular carcinogenesis
538-555页
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