Loss of Motor Protein MYO1C Causes Rhodopsin Mislocalization and Results in Impaired Visual Function.

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第一作者： Ashish K,Solanki

第一单位： Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.

作者： Ashish K,Solanki ^[1] ; Manas R,Biswal ^[2] ; Stephen,Walterhouse ^[1] ; René,Martin ^[3] ; Altaf A,Kondkar ^[4] ; Hans-Joachim,Knölker ^[3] ; Bushra,Rahman ^[1] ; Ehtesham,Arif ^[1] ; Shahid,Husain ^[5] ; Sandra R,Montezuma ^[6] ; Deepak,Nihalani ^[7] ; Glenn Prazere,Lobo ^[8]

作者单位： Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA. ^[1] Department of Pharmaceutical Sciences, Taneja College of Pharmacy, University of South Florida, Tampa, FL 33612, USA. ^[2] Faculty of Chemistry, Technische Universität Dresden, Bergstraße 66, 01069 Dresden, Germany. ^[3] Department of Ophthalmology, College of Medicine, King Saud University, Riyadh 11411, Saudi Arabia. ^[4] Department of Ophthalmology, Medical University of South Carolina, Charleston, SC 29425, USA. ^[5] Department of Ophthalmology and Visual Neurosciences, University of Minnesota, 516 Delaware Street S.E., 9th Floor, Minneapolis, MN 55455, USA. ^[6] National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bldg. 2DEM, Room 6085, 6707 Democracy Blvd., Bethesda, MD 20817, USA. ^[7] Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.;Department of Ophthalmology, Medical University of South Carolina, Charleston, SC 29425, USA.;Department of Ophthalmology and Visual Neurosciences, Lions Research Building, University of Minnesota, 2001 6th Street S.E., Room 225, Minneapolis, MN 55455, USA. ^[8]

关键词 motor protein myosin 1C outer segments photoreceptor retina rhodopsin visual function

主题词动物(Animals);动力蛋白(Dyneins);视网膜电描记术(Electroretinography);眼蛋白质类(Eye Proteins);小鼠(Mice);表型(Phenotype);光感受器细胞(Photoreceptor Cells);视网膜(Retina);视紫质(Rhodopsin)

DOI 10.3390/cells10061322

PMID 34073294

发布时间 2021-11-01

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2021年10卷6期

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Loss of Motor Protein MYO1C Causes Rhodopsin Mislocalization and Results in Impaired Visual Function.

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Loss of Motor Protein MYO1C Causes Rhodopsin Mislocalization and Results in Impaired Visual Function.

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