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SARS-CoV-2 Nsp14 activates NF-κB signaling and induces IL-8 upregulation.

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第一作者： Taiwei,Li

第一单位： Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

作者： Taiwei,Li ^[1] ; Adam D,Kenney ^[2] ; Helu,Liu ^[3] ; Guillaume N,Fiches ^[1] ; Dawei,Zhou ^[1] ; Ayan,Biswas ^[4] ; Jianwen,Que ^[3] ; Netty,Santoso ^[1] ; Jacob S,Yount ^[2] ; Jian,Zhu ^[5]

作者单位： Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. ^[1] Department of Microbial Infection and Immunity, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. ^[2] Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA. ^[3] Department of Genetics, The University of Alabama at Birmingham, Birmingham, AL 35233, USA. ^[4] Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.;Department of Microbial Infection and Immunity, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. ^[5]

关键词 IL-8 IMPDH2 NF-κB SARS-CoV-2 mycophenolic acid ribavirin

DOI 10.1101/2021.05.26.445787

PMID 34075374

发布时间 2024-09-23

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SARS-CoV-2 Nsp14 activates NF-κB signaling and induces IL-8 upregulation.

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SARS-CoV-2 Nsp14 activates NF-κB signaling and induces IL-8 upregulation.

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