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HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness.

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作者单位: Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. [1] Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, United States. [2] Center for Therapeutics Discovery, department of Oncological Sciences and Pharmacological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, United States. [3] Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, United States. [4] Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, United States. [5] IIGM (Italian Institute for Genomic Medicine), Torino, Italy. [6] Dipartimento di Scienze della Vita e Biologia dei Sistemi Università di Torino, Torino, Italy. [7] Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, Netherlands. [8] Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. [9] Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. [10] NTU Institute of Structural Biology, Nanyang Technological University, Singapore, Singapore. [11] Department of Medical Biophysics, University of Toronto, Toronto, Canada. [12] Princess Margaret Cancer Center, University Health Network, Toronto, Canada. [13] Ontario Institute for Cancer Research, Toronto, Canada. [14] Interdisciplinary Melanoma Cooperative Group, New York University Langone Medical Center, New York, United States. [15] Department of Pathology, New York University Langone Medical Center, New York, United States. [16] Department of Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, United States. [17] Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, United States. [18] Max Delbruck Center for Molecular Medicine, Berlin-Buch, Germany. [19] Department of Molecular Oncology, Moffitt Cancer Center, Tampa, United States. [20]
DOI 10.7554/eLife.59654
PMID 34075878
发布时间 2024-02-26
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