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Maximizing the potential of aggressive mouse tumor models in preclinical drug testing.

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作者单位: Baylor College of Medicine, Houston, TX, USA. [1] Department of Pathology, Texas Children's Hospital, Houston, TX, USA. [2] Humphrey Oei Institute of Cancer Research, National Cancer Center Singapore, Singapore, Singapore. [3] Pediatric Brain Tumor Research Office, SingHealth-Duke-NUS Academic Medical Center, Singapore, Singapore. [4] Division of Hematology-Oncology, Department of Pediatrics, Texas Children's Cancer Center, Houston, TX, USA. [5] Dan L. Duncan Cancer Center, Houston, TX, USA. [6] Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA. [7] Northwestern University Feinberg School of Medicine, Chicago, IL, USA. [8] Connecticut Children's Medical Center, The Jackson Laboratory for Genomic Medicine, University of Connecticut School of Medicine, Farmington, USA. [9] Department of Molecular Pathology, Texas Children's Hospital, Houston, TX, USA. [10] Departments of Pediatrics and Pathology, Children's Hospital Los Angeles, Norris Comprehensive Cancer Center, and the Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. [11] Institute of Molecular and Cell Biology, A*STAR, Singapore, Singapore. [12] Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore. [13] Baylor College of Medicine, Houston, TX, USA. wan-yee.teo@duke-nus.edu.sg. [14] Humphrey Oei Institute of Cancer Research, National Cancer Center Singapore, Singapore, Singapore. wan-yee.teo@duke-nus.edu.sg. [15] Pediatric Brain Tumor Research Office, SingHealth-Duke-NUS Academic Medical Center, Singapore, Singapore. wan-yee.teo@duke-nus.edu.sg. [16] Division of Hematology-Oncology, Department of Pediatrics, Texas Children's Cancer Center, Houston, TX, USA. wan-yee.teo@duke-nus.edu.sg. [17] Dan L. Duncan Cancer Center, Houston, TX, USA. wan-yee.teo@duke-nus.edu.sg. [18] Institute of Molecular and Cell Biology, A*STAR, Singapore, Singapore. wan-yee.teo@duke-nus.edu.sg. [19] Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore. wan-yee.teo@duke-nus.edu.sg. [20] KK Women's & Children's Hospital, Singapore, Singapore. wan-yee.teo@duke-nus.edu.sg. [21]
DOI 10.1038/s41598-021-91167-6
PMID 34079014
发布时间 2021-11-08
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