首页> Redox biology> Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy.

Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy.

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第一作者： Xiaojuan,Han

第一单位： Department of Rheumatology and Immunology, Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China; Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing, China; Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.

作者： Xiaojuan,Han ^[1] ; Tianshu,Xu ^[2] ; Qijun,Fang ^[2] ; Huajun,Zhang ^[2] ; Lijun,Yue ^[2] ; Gang,Hu ^[3] ; Lingyun,Sun ^[4]

作者单位： Department of Rheumatology and Immunology, Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China; Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing, China; Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China. ^[1] Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing, China. ^[2] Department of Pharmacology, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China. Electronic address: ghu@njmu.edu.cn. ^[3] Department of Rheumatology and Immunology, Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China; Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China. Electronic address: lingyunsun@nju.edu.cn. ^[4]

关键词 Microglia Mitophagy NLRP3 inflammasome Neuroinflammation Quercetin mtROS

医学主题词动物(Animals);炎性体(Inflammasomes);小鼠(Mice);小神经胶质细胞(Microglia);槲皮素(Quercetin);活性氧(Reactive Oxygen Species)

DOI 10.1016/j.redox.2021.102010

PMID 34082381

发布时间 2022-05-31

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准确一般字义偏差语意偏离译文作用小提交