Superior production of heavy pamamycin derivatives using a bkdR deletion mutant of Streptomyces albus J1074/R2.
作者:
主题词
3-甲基-2-氧代丁酸脱氢酶(硫辛酰胺)(3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide));细菌蛋白质类(Bacterial Proteins);生物合成途径(Biosynthetic Pathways);基因表达谱(Gene Expression Profiling);基因表达调控, 细菌(Gene Expression Regulation, Bacterial);基因, 细菌(Genes, Bacterial);工业微生物学(Industrial Microbiology);大环内酯类(Macrolides);代谢组(Metabolome);多基因族(Multigene Family);突变(Mutation);链霉菌属(Streptomyces);转录因子(Transcription Factors);缬氨酸(Valine)
DOI
10.1186/s12934-021-01602-6
PMID
34082758
发布时间
2021-10-18
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