SARS-CoV-2-specific CD8<sup>+</sup> T-cell responses and TCR signatures in the context of a prominent HLA-A*24:02 allomorph.

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作者： Louise C,Rowntree ^[1] ; Jan,Petersen ^[2] ; Jennifer A,Juno ^[3] ; Priyanka,Chaurasia ^[1] ; Kathleen,Wragg ^[2] ; Marios,Koutsakos ^[1] ; Luca,Hensen ^[1] ; Adam K,Wheatley ^[1] ; Stephen J,Kent ^[1] ; Jamie,Rossjohn ^[4] ; Katherine,Kedzierska ^[1] ; Thi Ho,Nguyen ^[4]

作者单位： Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia. ^[1] Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia. ^[2] Australian Research Council Centre of Excellence for Advanced Molecular Imaging, Monash University, Clayton, VIC 3800, Australia. ^[3] ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, University of Melbourne, Melbourne, VIC 3000, Australia. ^[4] Melbourne Sexual Health Centre, Infectious Diseases Department, Alfred Health, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia. ^[5] Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK. ^[6]

关键词 CD8+ T cells COVID-19 HLA-A*24:02 SARS-CoV-2 epitopes T-cell receptor

主题词 CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);人类(Humans);受体, 抗原, T细胞(Receptors, Antigen, T-Cell)

DOI 10.1111/imcb.12482

PMID 34086357

发布时间 2022-07-16

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