Intratumoral steroid profiling of adrenal cortisol-producing adenomas by liquid chromatography- mass spectrometry.

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作者： James P,Teuber ^[1] ; Kazutaka,Nanba ^[2] ; Adina F,Turcu ^[3] ; Xuan,Chen ^[4] ; Lili,Zhao ^[4] ; Tobias,Else ^[3] ; Richard J,Auchus ^[5] ; William E,Rainey ^[6] ; Juilee,Rege ^[7]

作者单位： Department of Pharmacology, University of Michigan, Ann Arbor, MI, 48109, USA. ^[1] Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, 48109, USA; Department of Endocrinology and Metabolism, National Hospital Organization Kyoto Medical Center, Kyoto, 612-8555, Japan. ^[2] Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA. ^[3] Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA. ^[4] Department of Pharmacology, University of Michigan, Ann Arbor, MI, 48109, USA; Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA. ^[5] Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, 48109, USA. ^[6] Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, 48109, USA. Electronic address: juilee@umich.edu. ^[7]

关键词 Cortisol-producing adenoma LC–MS/MS Mild autonomous cortisol excess OCT-embedded tissue Overt Cushing syndrome Steroid profiling