The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity.-论文-万方医学网

作者： Petra I,Lorenzo ^[1] ; Eugenia,Martin Vazquez ^[1] ; Livia,López-Noriega ^[1] ; Esther,Fuente-Martín ^[1] ; José M,Mellado-Gil ^[1] ; Jaime M,Franco ^[1] ; Nadia,Cobo-Vuilleumier ^[1] ; José A,Guerrero Martínez ^[1] ; Silvana Y,Romero-Zerbo ^[2] ; Jesús A,Perez-Cabello ^[1] ; Sabrina,Rivero Canalejo ^[3] ; Antonio,Campos-Caro ^[4] ; Christian Claude,Lachaud ^[1] ; Alejandra,Crespo Barreda ^[1] ; Manuel,Aguilar-Diosdado ^[4] ; Eduardo,García Fuentes ^[5] ; Alejandro,Martin-Montalvo ^[6] ; Manuel,Álvarez Dolado ^[1] ; Franz,Martin ^[1] ; Gemma,Rojo-Martinez ^[1] ; David,Pozo ^[7] ; Francisco J,Bérmudez-Silva ^[2] ; Valentine,Comaills ^[7] ; José C,Reyes ^[1] ; Benoit R,Gauthier ^[2]

作者单位： Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain. ^[1] Unidad de Gestión Clínica Intercentros de Endocrinología y Nutrición, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Spain. ^[2] Department of Normal and Pathological Histology and Cytology, University of Seville School of Medicine, Seville, Spain. ^[3] University Hospital "Puerta del Mar", Instituto de Investigación e Innovación en Ciencias Biomédicas de la Provincia de Cádiz (INiBICA), Cádiz, Spain. ^[4] Endocrinology and Metabolism Department, University Hospital "Puerta del Mar", Instituto de Investigación e Innovación en Ciencias Biomédicas de la Provincia de Cádiz (INiBICA), Cádiz, Spain. ^[5] Unidad de Gestión Clínica de Aparato Digestivo, Hospital Universitario Virgen de la Victoria, Instituto de Investigación Biomédica de Málaga (IBIMA), Spain. ^[6] Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain. ^[7]

主题词脂肪组织(Adipose Tissue);成年人(Adult);动物(Animals);星形细胞(Astrocytes);细胞存活(Cell Survival);辅阻遏蛋白质类(Co-Repressor Proteins);糖尿病, 2型(Diabetes Mellitus, Type 2);神经胶质原纤维酸性蛋白质(Glial Fibrillary Acidic Protein);神经胶质增生(Gliosis);葡萄糖(Glucose);高迁移率族蛋白质类(High Mobility Group Proteins);组蛋白脱甲基酶类(Histone Demethylases);人类(Humans);下丘脑(Hypothalamus);白细胞介素1β(Interleukin-1beta);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);中年人(Middle Aged);线粒体(Mitochondria);神经组织蛋白质类(Nerve Tissue Proteins);神经元(Neurons);肥胖症(Obesity);RNA, 小分子干扰(RNA, Small Interfering)

DOI 10.7150/thno.57237

PMID 34093866

发布时间 2024-04-02

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The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity.

Theranostics

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The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity.

Theranostics

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Theranostics

相关期刊

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