Tumor-Specific Delivery of 5-Fluorouracil-Incorporated Epidermal Growth Factor Receptor-Targeted Aptamers as an Efficient Treatment in Pancreatic Ductal Adenocarcinoma Models.-论文-万方医学网

第一作者： Ujjwal M,Mahajan

第一单位： Department of Medicine II, University Hospital, LMU Munich, Munich, Germany.

作者： Ujjwal M,Mahajan ^[1] ; Qi,Li ^[1] ; Ahmed,Alnatsha ^[1] ; Jessica,Maas ^[2] ; Michael,Orth ^[2] ; Sebastian Hubertus,Maier ^[2] ; Julian,Peterhansl ^[1] ; Ivonne,Regel ^[1] ; Matthias,Sendler ^[3] ; Preshit R,Wagh ^[3] ; Neha,Mishra ^[3] ; Yonggan,Xue ^[1] ; Prince,Allawadhi ^[1] ; Georg,Beyer ^[1] ; Jens-Peter,Kühn ^[4] ; Thomas,Marshall ^[3] ; Bettina,Appel ^[5] ; Felix,Lämmerhirt ^[3] ; Claus,Belka ^[2] ; Sabine,Müller ^[5] ; Frank-Ulrich,Weiss ^[3] ; Kirsten,Lauber ^[2] ; Markus M,Lerch ^[6] ; Julia,Mayerle ^[7]

作者单位： Department of Medicine II, University Hospital, LMU Munich, Munich, Germany. ^[1] Department of Radiation Oncology, Hospital of Ludwig-Maximilians-University, Munich, Germany. ^[2] Department of Medicine A, University Medicine Greifswald, Greifswald, Germany. ^[3] Institute and Policlinic of Diagnostic and Interventional Radiology, Medical University, Carl-Gustav-Carus, Dresden, Germany. ^[4] Institute of Biochemistry, University Greifswald, Germany. ^[5] Department of Medicine A, University Medicine Greifswald, Greifswald, Germany; LMU Klinikum, Munich, Germany. ^[6] Department of Medicine II, University Hospital, LMU Munich, Munich, Germany; Department of Medicine A, University Medicine Greifswald, Greifswald, Germany. Electronic address: julia.mayerle@med.uni-muenchen.de. ^[7]

医学主题词动物(Animals);抗代谢药, 抗肿瘤(Antimetabolites, Antineoplastic);适体, 核苷(Aptamers, Nucleotide);癌, 胰腺管(Carcinoma, Pancreatic Ductal);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);药物释放系统(Drug Delivery Systems);抗药性, 肿瘤(Drug Resistance, Neoplasm);胞吞作用(Endocytosis);女(雌)性(Female);氟尿嘧啶(Fluorouracil);人类(Humans);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);类器官(Organoids);胰腺肿瘤(Pancreatic Neoplasms);SELEX适体技术(SELEX Aptamer Technique);肿瘤负荷(Tumor Burden);肿瘤细胞, 培养的(Tumor Cells, Cultured);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays);小鼠(Mice)

DOI 10.1053/j.gastro.2021.05.055

PMID 34097885

发布时间 2024-02-26

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Tumor-Specific Delivery of 5-Fluorouracil-Incorporated Epidermal Growth Factor Receptor-Targeted Aptamers as an Efficient Treatment in Pancreatic Ductal Adenocarcinoma Models.

Gastroenterology

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Tumor-Specific Delivery of 5-Fluorouracil-Incorporated Epidermal Growth Factor Receptor-Targeted Aptamers as an Efficient Treatment in Pancreatic Ductal Adenocarcinoma Models.

Gastroenterology

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同项目论文

Gastroenterology

相关期刊

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