Model-based control for column-based continuous viral inactivation of biopharmaceuticals.

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作者： Moo Sun,Hong ^[1] ; Amos E,Lu ^[1] ; Rui Wen,Ou ^[2] ; Jacqueline M,Wolfrum ^[3] ; Stacy L,Springs ^[3] ; Anthony J,Sinskey ^[2] ; Richard D,Braatz ^[1]

作者单位： Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. ^[1] Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. ^[2] Center for Biomedical Innovation, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. ^[3]

关键词 bioprocess engineering continuous processing viral inactivation

主题词生物制品(Biological Products);人类(Humans);氢离子浓度(Hydrogen-Ion Concentration);模型, 化学(Models, Chemical);病毒灭活(Virus Inactivation)

DOI 10.1002/bit.27846

PMID 34101159

发布时间 2024-07-02

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