Serum PreS1 and HBsAg ratio reflects liver fibrosis and predicts the development of hepatocellular carcinoma in chronic hepatitis B patients.

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第一作者： Yuno,Nishida

第一单位： Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Science, Hiroshima, Japan.

作者： Yuno,Nishida ^[1] ; Michio,Imamura ^[2] ; Yuji,Teraoka ^[1] ; Kei,Morio ^[2] ; Hatsue,Fujino ^[1] ; Atsushi,Ono ^[2] ; Takashi,Nakahara ^[1] ; Eisuke,Murakami ^[2] ; Masami,Yamauchi ^[1] ; Tomokazu,Kawaoka ^[2] ; Daiki,Miki ^[1] ; Masataka,Tsuge ^[2] ; Akira,Hiramatsu ^[1] ; Hiromi,Abe-Chayama ^[2] ; C Nelson,Hayes ^[1] ; Hiroshi,Aikata ^[2] ; Noriko,Sasaki ^[1] ; Tomomi,Sekiguchi ^[2] ; Hideki,Kinukawa ^[1] ; Toru,Yoshimura ^[2] ; Kazuaki,Chayama ^[1]

作者单位： Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Science, Hiroshima, Japan. ^[1] Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan. ^[2] Natural Science Center for Basic Research and Development, Hiroshima University, Hiroshima, Japan. ^[3] Center for Medical Specialist Graduate Education and Research, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan. ^[4] Diagnostics Division, Abbott Japan LLC, Matsudo, Japan. ^[5] Collaborative Research Laboratory of Medical Innovation, Graduate School of Biomedical and Health Sciences, Hiroshima University, Yokohama, Japan. ^[6] Institute of Physical and Chemical Research (RIKEN) Center for Integrative Medical Sciences, Yokohama, Japan. ^[7]

关键词 PreS1 hepatitis B core-related antigen hepatitis B virus hepatocellular carcinoma large hepatitis B surface