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Human Three Prime Repair Exonuclease 1 Promotes HIV-1 Integration by Preferentially Degrading Unprocessed Viral DNA.

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第一作者： Benem-Orom,Davids

第一单位： Center for AIDS Health Disparities Research, Meharry Medical Collegegrid.259870.1, Nashville, Tennessee, USA.;Department of Biochemistry, Cancer Biology, Pharmacology and Neuroscience, Meharry Medical Collegegrid.259870.1, Nashville, Tennessee, USA.

作者： Benem-Orom,Davids ^[1] ; Muthukumar,Balasubramaniam ^[1] ; Nicklas,Sapp ^[1] ; Prem,Prakash ^[1] ; Shalonda,Ingram ^[2] ; Min,Li ^[3] ; Robert,Craigie ^[3] ; Thomas,Hollis ^[4] ; Jui,Pandhare ^[5] ; Chandravanu,Dash ^[1]

作者单位： Center for AIDS Health Disparities Research, Meharry Medical Collegegrid.259870.1, Nashville, Tennessee, USA.;Department of Biochemistry, Cancer Biology, Pharmacology and Neuroscience, Meharry Medical Collegegrid.259870.1, Nashville, Tennessee, USA. ^[1] Department of Biochemistry, Cancer Biology, Pharmacology and Neuroscience, Meharry Medical Collegegrid.259870.1, Nashville, Tennessee, USA. ^[2] Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA. ^[3] Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA. ^[4] Center for AIDS Health Disparities Research, Meharry Medical Collegegrid.259870.1, Nashville, Tennessee, USA.;Department of Microbiology, Immunology, and Physiology, Meharry Medical Collegegrid.259870.1, Nashville, Tennessee, USA.;School of Graduate Studies and Research, Meharry Medical Collegegrid.259870.1, Nashville, Tennessee, USA. ^[5]

关键词 HIV PIC TREX1 Three prime repair exonuclease 1 exonuclease human immunodeficiency virus intasome integration preintegration complex reverse transcription