Total Synthesis and Antimalarial Activity of 2-(<i>p</i>-Hydroxybenzyl)-prodigiosins, Isoheptylprodigiosin, and Geometric Isomers of Tambjamine MYP1 Isolated from Marine Bacteria.

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作者： Papireddy,Kancharla ^[1] ; Yuexin,Li ^[2] ; Monish,Yeluguri ^[1] ; Rozalia A,Dodean ^[2] ; Kevin A,Reynolds ^[1] ; Jane X,Kelly ^[1]

作者单位： Department of Chemistry, Portland State University, Portland, Oregon 97201, United States. ^[1] Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States. ^[2]

主题词动物(Animals);抗疟药(Antimalarials);女(雌)性(Female);Hep G2细胞(Hep G2 Cells);人类(Humans);小鼠(Mice);分子结构(Molecular Structure);寄生虫敏感性试验(Parasitic Sensitivity Tests);恶性疟原虫(Plasmodium falciparum);约氏疟原虫(Plasmodium yoelii);灵菌红素(Prodigiosin);吡咯类(Pyrroles);立体异构现象(Stereoisomerism);构效关系(Structure-Activity Relationship)

DOI 10.1021/acs.jmedchem.1c00748

PMID 34111350

发布时间 2021-12-14

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Journal of medicinal chemistry

2021年64卷12期

8739-8754页

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Total Synthesis and Antimalarial Activity of 2-(<i>p</i>-Hydroxybenzyl)-prodigiosins, Isoheptylprodigiosin, and Geometric Isomers of Tambjamine MYP1 Isolated from Marine Bacteria.

Journal of medicinal chemistry

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Journal of medicinal chemistry

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Total Synthesis and Antimalarial Activity of 2-(<i>p</i>-Hydroxybenzyl)-prodigiosins, Isoheptylprodigiosin, and Geometric Isomers of Tambjamine MYP1 Isolated from Marine Bacteria.

Journal of medicinal chemistry

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Journal of medicinal chemistry

相关期刊

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