Priming of pancreatic cancer cells with bispecific antibody armed activated T cells sensitizes tumors for enhanced chemoresponsiveness.

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作者： Archana,Thakur ^[1] ; Johnson,Ung ^[1] ; Elyse N,Tomaszewski ^[2] ; Amy,Schienschang ^[1] ; Timothy M,LaBrie ^[1] ; Dana L,Schalk ^[1] ; Lawrence G,Lum ^[1]

作者单位： Department of Medicine, Division of Hematology and Oncology, University of Virginia Cancer Center, Charlottesville, Virginia, USA. ^[1] Department of Oncology, Barbara Ann Karmanos Cancer Institute and Wayne State University, Detroit, Michigan, USA. ^[2]

关键词 Chemoresponsiveness bispecific antibody armed activated T cells chemosensitization pancreatic cancer

主题词抗体, 双特异性(Antibodies, Bispecific);人类(Humans);肿瘤干细胞(Neoplastic Stem Cells);胰腺肿瘤(Pancreatic Neoplasms);T淋巴细胞(T-Lymphocytes)

DOI 10.1080/2162402X.2021.1930883

PMID 34123574

发布时间 2024-12-03

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