Exploring clinical and gene expression markers of benefit from FOLFOXIRI/bevacizumab in patients with BRAF-mutated metastatic colorectal cancer: Subgroup analyses of the TRIBE2 study.

导出 LinkOut

翻译打印收藏纠错

第一作者： Roberto,Moretto

第一单位： Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.

作者： Roberto,Moretto ^[1] ; Mirella,Giordano ^[2] ; Anello M,Poma ^[3] ; Alessandro,Passardi ^[4] ; Alessandra,Boccaccino ^[5] ; Filippo,Pietrantonio ^[6] ; Gianluca,Tomasello ^[7] ; Giuseppe,Aprile ^[8] ; Sara,Lonardi ^[9] ; Veronica,Conca ^[5] ; Cristina,Granetto ^[10] ; Antonio,Frassoldati ^[11] ; Matteo,Clavarezza ^[12] ; Alessandro S,Bertolini ^[13] ; Marco M,Germani ^[5] ; Clara,Ugolini ^[3] ; Gabriella,Fontanini ^[3] ; Gianluca,Masi ^[5] ; Alfredo,Falcone ^[5] ; Chiara,Cremolini ^[14]

作者单位： Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy. ^[1] Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa, Pisa, Italy. ^[2] Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy. ^[3] Department of Medical Oncology, IRCCS Istituto Romagnolo per Lo Studio Dei Tumori (IRST) "Dino Amadori", Meldola, Italy. ^[4] Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy; Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa, Pisa, Italy. ^[5] Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Oncology and Hemato-oncology Department, University of Milan, Milan, Italy. ^[6] Oncology Unit, Oncology Department, ASST of Cremona, Cremona, Italy; UOC Medical Oncology, IRCCS Foundation Ca' Granda Maggiore Hospital Policlinic, Milan, Italy. ^[7] Department of Oncology, University and General Hospital, Udine, Italy; Department of Oncology, San Bortolo General Hospital, Vicenza, Italy. ^[8] Early Phase Clinical Trial Unit, Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy; Medical Oncology Unit 1, Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy. ^[9] Medical Oncology, Azienda Ospedaliera S., Croce e Carle Ospedale di Insegnamento, Cuneo, Italy. ^[10] Clinical Oncology, Oncology Department, Azienda Ospedaliero Universitaria di Ferrara, Ferrara, Italy. ^[11] Medical Oncology, Ente Ospedaliero Ospedali Galliera, Genova, Italy. ^[12] Medical Oncology, ASST Della Valtellina e Alto Lario, Sondrio, Italy. ^[13] Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy; Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa, Pisa, Italy. Electronic address: chiaracremolini@gmail.com. ^[14]

关键词 BM1/BM2 subtypes BRAF-mutant FOLFOXIRI/bevacizumab LI/LD-Wnt pathway Metastatic colorectal cancer