Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19: the PROFLO multicenter randomized clinical trial.

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第一作者： Jacob,Rosén

第一单位： Department of Surgical Sciences, Section of Anaesthesiology and Intensive Care Medicine, Uppsala University, Entrance 78, 1 floor, 751 85, Uppsala, Sweden. jacob.rosen@surgsci.uu.se.

作者： Jacob,Rosén ^[1] ; Erik,von Oelreich ^[2] ; Diddi,Fors ^[3] ; Malin,Jonsson Fagerlund ^[4] ; Knut,Taxbro ^[2] ; Paul,Skorup ^[3] ; Ludvig,Eby ^[5] ; Francesca,Campoccia Jalde ^[6] ; Niclas,Johansson ^[7] ; Gustav,Bergström ^[2] ; Peter,Frykholm ^[8] ; PROFLO Study Group ^[9]

作者单位： Department of Surgical Sciences, Section of Anaesthesiology and Intensive Care Medicine, Uppsala University, Entrance 78, 1 floor, 751 85, Uppsala, Sweden. jacob.rosen@surgsci.uu.se. ^[1] Perioperative Medicine and Intensive Care, Karolinska University Hospital, Solna, Sweden. ^[2] Department of Physiology and Pharmacology, Section of Anesthesiology and Intensive Care Medicine, Karolinska Institutet, Solna, Sweden. ^[3] Department of Surgical Sciences, Section of Anaesthesiology and Intensive Care Medicine, Uppsala University, Entrance 78, 1 floor, 751 85, Uppsala, Sweden. ^[4] Department of Anaesthesiology and Intensive Care Medicine, Ryhov County Hospital, Jönköping, Sweden. ^[5] Department of Medical Sciences, Section of Infectious Diseases, Uppsala University, Uppsala, Sweden. ^[6] Acute and Reparative Medicine, Karolinska University Hospital, Solna, Sweden. ^[7] Department of Molecular Medicine and Surgery, Section of Thoracic Anesthesiology and Intensive Care, Karolinska Institutet, Solna, Sweden. ^[8] Department of Infectious Diseases, Karolinska University Hospital, Solna, Sweden. ^[9] Infectious Diseases Unit, Department of Medicine, Karolinska Institutet, Solna, Sweden. ^[10]

关键词 Awake prone positioning COVID-19 Critical care High-flow nasal oxygen Intensive care Intubation rates Mechanical ventilation Noninvasive ventilation Respiratory failure