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Pharmacogenetics to Avoid Loss of Hearing (PALOH) trial: a protocol for a prospective observational implementation trial.

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第一作者： John Henry,McDermott

第一单位： Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK john.mcdermott2@mft.nhs.uk.;Division of Evolution and Genomic Sciences, The University of Manchester, Manchester, UK.

作者： John Henry,McDermott ^[1] ; Rachel,Mahood ^[2] ; Duncan,Stoddard ^[3] ; Ajit,Mahaveer ^[4] ; Mark A,Turner ^[5] ; Rachel,Corry ^[2] ; Julia,Garlick ^[2] ; Gino,Miele ^[6] ; Shaun,Ainsworth ^[6] ; Laura,Kemp ^[6] ; Iain,Bruce ^[7] ; Richard,Body ^[8] ; Fiona,Ulph ^[9] ; Rhona,Macleod ^[2] ; Karen,Harvey ^[5] ; Nicola,Booth ^[4] ; Peter,Roberts ^[10] ; Paul,Wilson ^[11] ; William G,Newman ^[12]

作者单位： Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK john.mcdermott2@mft.nhs.uk.;Division of Evolution and Genomic Sciences, The University of Manchester, Manchester, UK. ^[1] Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK. ^[2] Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK.;DS Analytics and Machine Learning Ltd, London, UK. ^[3] Neonatal Intensive Care Unit, Manchester University NHS Foundation Trust, Manchester, UK. ^[4] Neonatal Intensive Care Unit, Liverpool Women's Hospital NHS Foundation Trust, Liverpool, UK. ^[5] Genedrive plc, Manchester, UK. ^[6] Paediatric ENT Department, Manchester University Hospitals NHS Foundation Trust, Manchester, UK. ^[7] Emergency Department, Manchester University NHS Foundation Trust, Manchester, UK.;Division of Cardiovascular Sciences, The University of Manchester, Manchester, Manchester, UK. ^[8] Division of Psychology & Mental Health, University of Manchester, Manchester, UK. ^[9] Market Access & Reimbursement Solutions, Manchester, UK. ^[10] Alliance Manchester Business School, University of Manchester, Manchester, UK. ^[11] Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK.;Division of Evolution and Genomic Sciences, The University of Manchester, Manchester, UK. ^[12]

关键词 adverse events audiology genetics neonatal intensive & critical care preventive medicine

医学主题词聋(Deafness);听力(Hearing);人类(Humans);婴儿, 新生(Infant, Newborn);遗传药理学(Pharmacogenetics);前瞻性研究(Prospective Studies)

DOI 10.1136/bmjopen-2020-044457

PMID 34135034

发布时间 2025-05-30

基金项目

II-LB-0417-20002/DH_/Department of Health/United Kingdom

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