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Learning the protein language: Evolution, structure, and function.

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第一作者： Tristan,Bepler

第一单位： Simons Machine Learning Center, New York Structural Biology Center, New York, NY, USA; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA; Computational and Systems Biology Program, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address: tbepler@nysbc.org.

作者： Tristan,Bepler ^[1] ; Bonnie,Berger ^[2]

作者单位： Simons Machine Learning Center, New York Structural Biology Center, New York, NY, USA; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA; Computational and Systems Biology Program, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address: tbepler@nysbc.org. ^[1] Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA; Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address: bab@mit.edu. ^[2]

关键词 contact prediction deep neural networks inductive bias language models natural language processing protein sequences proteins transfer learning transmembrane region prediction

医学主题词氨基酸序列(Amino Acid Sequence);数据库, 蛋白质(Databases, Protein);语言(Language);蛋白质类(Proteins)

DOI 10.1016/j.cels.2021.05.017

PMID 34139171

发布时间 2024-08-12

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