Discovery of eight alkaloids with D1 and D2 antagonist activity in leaves of Nelumbo nucifera Gaertn. Using FLIPR assays.

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作者： Han,Zhou ^[1] ; Tao,Hou ^[2] ; Zhenhua,Gao ^[3] ; Xiujie,Guo ^[4] ; Chaoran,Wang ^[5] ; Jixia,Wang ^[6] ; Yanfang,Liu ^[1] ; Xinmiao,Liang ^[1]

作者单位： CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China. ^[1] CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China; DICP-CMC Innovation Institute of Medicine, Taizhou, 225300, China. ^[2] Department of Chemistry and Environmental Engineering, Hubei Minzu University, Enshi, 445000, China. ^[3] DICP-CMC Innovation Institute of Medicine, Taizhou, 225300, China. ^[4] CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China; DICP-CMC Innovation Institute of Medicine, Taizhou, 225300, China. Electronic address: wangchaoran@castim.cn. ^[5] CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China. Electronic address: jxwang@dicp.ac.cn. ^[6]

关键词 Alkaloids Dopamine D1 receptor Dopamine D2 receptor Lotus leaves Nelumbo nucifera Gaertn.