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Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes.

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第一作者: Anna,Esteve-Codina
第一单位: CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.;Universitat Pompeu Fabra (UPF), Barcelona, Spain.
作者单位: CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.;Universitat Pompeu Fabra (UPF), Barcelona, Spain. [1] EvA Study Center, Helmholtz Zentrum Muenchen and Asklepios-Klinik, Gauting, Germany.;Immunoanalytics-Core Facility, Helmholtz Zentrum Muenchen, Munich, Germany. [2] EvA Study Center, Helmholtz Zentrum Muenchen and Asklepios-Klinik, Gauting, Germany. [3] Centre National de Recherche en Génomique Humaine (CNRGH), Institut de Biologie François Jacob, CEA, Université Paris-Saclay, Evry, France. [4] Institute for Lung Biology and Disease, Helmholtz Zentrum Muenchen, Neuherberg-Munich, Germany. [5] Internal Medicine III, University Hospital Regensburg, Regensburg, Germany. [6] Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.;Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.;Member of the German Center for Lung Research (DZL), Hannover, Germany. [7] Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.;Member of the German Center for Lung Research (DZL), Hannover, Germany. [8] Member of the German Center for Lung Research (DZL), Marburg, Germany.;Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg, Philipps-University, Marburg, Germany. [9] Department of Pneumology, Faculty of Medicine, University of Freiburg, Freiburg, Germany. [10] Institute for Lung Health, NIHR Leicester BRC, University of Leicester, Leicester, UK. [11] Department of Respiratory Medicine, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK. [12] Medicines Evaluation Unit, University of Manchester, University Hospital of South Manchester Foundations Trust, Manchester, UK. [13] Department of Pathophysiology, National Koranyi Institute for TB and Pulmonology, Budapest, Hungary. [14] Department of Tumorbiology, National Koranyi Institute for TB and Pulmonology, Budapest, Hungary. [15] Department of Pneumology, National Koranyi Institute for TB and Pulmonology, Budapest, Hungary. [16] Department of Medical Sciences, University of Ferrara and Ferrara City Hospital, Ferrara, Italy. [17] 2nd Department of Respiratory Medicine, National Institute of Tuberculosis and Lung Diseases, Warsaw, Poland. [18] ICT Department, Helmholtz Zentrum Muenchen, Munich, Germany. [19] Department Strategy & Digitalization, Helmholtz Zentrum Muenchen, Munich, Germany.;Faculty of Mathematics, Technical University of Munich, Munich, Germany. [20] Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands. [21] Department of Medical Sciences, University of Uppsala, Uppsala, Sweden. [22] Immunoanalytics-Tissue Control of Immunocytes, Helmholtz Zentrum Muenchen, Munich, Germany. [23] EvA Study Center, Helmholtz Zentrum Muenchen and Asklepios-Klinik, Gauting, Germany. Loems-EvA@gmx.de. [24]
DOI 10.1038/s41598-021-91742-x
PMID 34145303
发布时间 2021-12-04
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