Identifying novel genetic variants for brain amyloid deposition: a genome-wide association study in the Korean population.
作者:
Hang-Rai,Kim [1]
;
Sang-Hyuk,Jung [2]
;
Jaeho,Kim [3]
;
Hyemin,Jang [4]
;
Sung Hoon,Kang [5]
;
Song,Hwangbo [4]
;
Jun Pyo,Kim [6]
;
So Yeon,Kim [7]
;
Beomsu,Kim [8]
;
Soyeon,Kim [8]
;
Jee Hyang,Jeong [9]
;
Soo Jin,Yoon [10]
;
Kyung Won,Park [11]
;
Eun-Joo,Kim [12]
;
Bora,Yoon [13]
;
Jae-Won,Jang [14]
;
Jin Yong,Hong [15]
;
Seong Hye,Choi [16]
;
Young,Noh [17]
;
Ko Woon,Kim [18]
;
Si Eun,Kim [19]
;
Jin San,Lee [20]
;
Na-Yeon,Jung [21]
;
Juyoun,Lee [22]
;
Byeong C,Kim [23]
;
Sang Joon,Son [24]
;
Chang Hyung,Hong [24]
;
Duk L,Na [25]
;
Sang Won,Seo [26]
;
Hong-Hee,Won [27]
;
Hee Jin,Kim [28]
作者单位:
Department of Neurology, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Republic of Korea.;Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.;Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea.
[1]
Department of Digital Health, SAIHST, Sungkyunkwan University, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.;Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.
[2]
Department of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Republic of Korea.
[3]
Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.;Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea.
[4]
Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.;Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea.;Department of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
[5]
Center for Neuroimaging, Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.
[6]
Department of Digital Health, SAIHST, Sungkyunkwan University, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.;Samsung Genome Institute, Samsung Medical Center, Seoul, Republic of Korea.
[7]
Department of Digital Health, SAIHST, Sungkyunkwan University, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
[8]
Department of Neurology, Ewha Womans University Seoul Hospital, Ewha Womans University School of Medicine, Seoul, Republic of Korea.
[9]
Department of Neurology, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Republic of Korea.
[10]
Department of Neurology, Dong-A University College of Medicine, Department of Translational Biomedical Sciences, Graduate School of Dong-A University, Busan, Republic of Korea.
[11]
Department of Neurology, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Busan, Republic of Korea.
[12]
Department of Neurology, Konyang University College of Medicine, Daejeon, Republic of Korea.
[13]
Department of Neurology, Kangwon National University Hospital, Kangwon National University College of Medicine, Chuncheon, Republic of Korea.
[14]
Department of Neurology, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
[15]
Department of Neurology, Inha University School of Medicine, Incheon, Republic of Korea.
[16]
Department of Neurology, Gachon University College of Medicine, Gil Medical Center, Incheon, Republic of Korea.
[17]
Department of Neurology, School of Medicine, Jeonbuk National University Hospital, Jeonju, Republic of Korea.
[18]
Department of Neurology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Republic of Korea.
[19]
Department of Neurology, Kyung Hee University College of Medicine, Kyung Hee University Hospital, Seoul, Republic of Korea.
[20]
Department of Neurology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine and Medical Research Institute, Busan, Republic of Korea.
[21]
Department of Neurology, Chungnam National University Hospital, Daejeon, Republic of Korea.
[22]
Departmet of Neurology, Chonnam National University School of Medicine, Gwangju, Republic of Korea.
[23]
Department of Psychiatry, Ajou University School of Medicine, Suwon, Republic of Korea.
[24]
Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.;Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea.;Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea.
[25]
Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.;Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea.;Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea.;Department of Intelligent Precision Healthcare Convergence, Sungkyunkwan University, Seoul, Republic of Korea.
[26]
Department of Digital Health, SAIHST, Sungkyunkwan University, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea. wonhh@skku.edu.;Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea. wonhh@skku.edu.
[27]
Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea. evekhj@gmail.com.;Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea. evekhj@gmail.com.;Department of Digital Health, SAIHST, Sungkyunkwan University, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea. evekhj@gmail.com.;Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea. evekhj@gmail.com.
[28]
主题词
阿尔茨海默病(Alzheimer Disease);淀粉样β肽类(Amyloid beta-Peptides);脑(Brain);纤维蛋白原(Fibrinogen);全基因组关联研究(Genome-Wide Association Study);人类(Humans);正电子发射断层显像术(Positron-Emission Tomography);韩国(Republic of Korea)
DOI
10.1186/s13195-021-00854-z
PMID
34154648
发布时间
2024-08-12
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Alzheimer's research & therapy
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