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KRAS-driven model of Gorham-Stout disease effectively treated with trametinib.

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第一作者： Nassim,Homayun-Sepehr

第一单位： Human Molecular Genetics, de Duve Institute, University of Louvain, Brussels, Belgium.

作者： Nassim,Homayun-Sepehr ^[1] ; Anna L,McCarter ^[2] ; Raphaël,Helaers ^[1] ; Christine,Galant ^[3] ; Laurence M,Boon ^[4] ; Pascal,Brouillard ^[1] ; Miikka,Vikkula ^[5] ; Michael T,Dellinger ^[6]

作者单位： Human Molecular Genetics, de Duve Institute, University of Louvain, Brussels, Belgium. ^[1] Division of Surgical Oncology, Department of Surgery and Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, Dallas, Texas, USA. ^[2] Center for Vascular Anomalies, Division of Pathology, and. ^[3] Human Molecular Genetics, de Duve Institute, University of Louvain, Brussels, Belgium.;Division of Plastic Surgery, Cliniques universitaires Saint-Luc, University of Louvain, European Reference Network for Rare Multisystemic Vascular Diseases, Vascular Anomalies Working Group, European Reference Centre, Brussels, Belgium. ^[4] Human Molecular Genetics, de Duve Institute, University of Louvain, Brussels, Belgium.;Division of Plastic Surgery, Cliniques universitaires Saint-Luc, University of Louvain, European Reference Network for Rare Multisystemic Vascular Diseases, Vascular Anomalies Working Group, European Reference Centre, Brussels, Belgium.;Walloon Excellence in Life Sciences and Biotechnology, University of Louvain, Brussels, Belgium. ^[5] Division of Surgical Oncology, Department of Surgery and Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, Dallas, Texas, USA.;Department of Molecular Biology and Hamon Center for Regenerative Science and Medicine, UT Southwestern Medical Center, Dallas, Texas, USA. ^[6]

关键词 Angiogenesis Bone disease Molecular genetics Vascular Biology