Analysis of Immune Landscape in Pancreatic and Ileal Neuroendocrine Tumours Demonstrates an Immune Cold Tumour Microenvironment.

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作者： Lulu,Tanno ^[1] ; Salma,Naheed ^[2] ; Jonathan,Dunbar ^[1] ; Jo,Tod ^[3] ; Maria A,Lopez ^[4] ; Julian,Taylor ^[5] ; Maria,Machado ^[6] ; Bryan,Green ^[6] ; Margaret,Ashton-Key ^[6] ; Serena J,Chee ^[7] ; Oliver,Wood ^[1] ; Neil W,Pearce ^[7] ; Gareth J,Thomas ^[1] ; Peter S,Friedmann ^[1] ; Judith,Cave ^[2] ; Christian H,Ottensmeier ^[1]

作者单位： School of Cancer Sciences, and CRUK and NIHR Experimental Cancer Medicine Centre, University of Southampton, Southampton, UK. ^[1] Department of Hepato-Pancreato-Biliary Surgery, University Hospital Southampton NHS Foundation Trust, Southampton, UK. ^[2] Department of Medical Oncology, University Hospital Southampton NHS Foundation Trust, Southampton, UK. ^[3] Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK. ^[4] Department of Gastroenterology, University Hospitals Dorset NHS Foundation Trust, Bournemouth, UK. ^[5] Department of Research Histology, University of Southampton, Southampton, UK. ^[6] Department of Histopathology, University Hospital Southampton NHS Foundation Trust, Southampton, UK. ^[7] Division of Clinical and Experimental Sciences, Sir Henry Wellcome Laboratories, University of Southampton, Southampton, UK. ^[8] Department of Molecular & Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK. ^[9]

关键词 Ileal neuroendocrine tumour Pancreatic neuroendocrine tumour Tumour-infiltrating lymphocytes

主题词人类(Humans);神经内分泌瘤(Neuroendocrine Tumors);胰腺肿瘤(Pancreatic Neoplasms);预后(Prognosis);胃肿瘤(Stomach Neoplasms);肿瘤微环境(Tumor Microenvironment)

DOI 10.1159/000517688

PMID 34157710

发布时间 2024-04-12

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