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A SARS-CoV-2 spike ferritin nanoparticle vaccine protects against heterologous challenge with B.1.1.7 and B.1.351 virus variants in Syrian golden hamsters.

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作者单位: U.S. Military HIV Research Program, Center for Infectious Diseases Research, Walter Reed Army Institute of Research, Silver Spring, Maryland USA. [1] Veterinary Pathology Division, Walter Reed Army Institute of Research, Silver Spring, Maryland USA. [2] Emerging Infectious Diseases Branch, Center for Infectious Diseases Research, Walter Reed Army Institute of Research, Silver Spring, Maryland USA. [3] Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland USA. [4] Diagnostics Countermeasures Branch, Center for Infectious Diseases Research, Walter Reed Army Institute of Research, Silver Spring, Maryland USA. [5] Virus Diseases Branch, Center for Infectious Diseases Research, Walter Reed Army Institute of Research, Silver Spring, Maryland USA. [6] Oak Ridge Institute of Science and Education, Oak Ridge, Tennessee USA. [7] Pathology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland USA. [8] Pilot Bioproduction Facility, Walter Reed Army Institute of Research, Silver Spring, Maryland USA. [9] Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland USA. [10] Virus Persistence and Dynamics Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland USA. [11] W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland USA. [12] BioQual, Inc., Rockville, Maryland USA. [13] Emory Vaccine Center, Department of Pediatrics, Emory School of Medicine, Atlanta, Georgia USA. [14] Cellular Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland USA. [15] One Health Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland USA. [16] These authors contributed equally. [17] Center for Infectious Diseases Research, Walter Reed Army Institute of Research, Silver Spring, Maryland USA. [18]
DOI 10.1101/2021.06.16.448525
PMID 34159328
发布时间 2023-11-07
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