作者:
Min-A,Jhun [1]
;
Michael,Mendelson [2]
;
Rory,Wilson [3]
;
Rahul,Gondalia [4]
;
Roby,Joehanes [5]
;
Elias,Salfati [6]
;
Xiaoping,Zhao [7]
;
Kim Valeska Emilie,Braun [8]
;
Anh Nguyet,Do [9]
;
Åsa K,Hedman [10]
;
Tao,Zhang [11]
;
Elena,Carnero-Montoro [12]
;
Jincheng,Shen [13]
;
Traci M,Bartz [14]
;
Jennifer A,Brody [15]
;
May E,Montasser [16]
;
Jeff R,O'Connell [16]
;
Chen,Yao [17]
;
Rui,Xia [7]
;
Eric,Boerwinkle [18]
;
Megan,Grove [18]
;
Weihua,Guan [19]
;
Pfeiffer,Liliane [3]
;
Paula,Singmann [3]
;
Martina,Müller-Nurasyid [20]
;
Thomas,Meitinger [21]
;
Christian,Gieger [3]
;
Annette,Peters [22]
;
Wei,Zhao [23]
;
Erin B,Ware [24]
;
Jennifer A,Smith [24]
;
Klodian,Dhana [25]
;
Joyce,van Meurs [26]
;
Andre,Uitterlinden [26]
;
Mohammad Arfan,Ikram [8]
;
Mohsen,Ghanbari [8]
;
Deugi,Zhi [27]
;
Stefan,Gustafsson [10]
;
Lars,Lind [10]
;
Shengxu,Li [11]
;
Dianjianyi,Sun [28]
;
Tim D,Spector [29]
;
Yii-der Ida,Chen [30]
;
Coleen,Damcott [16]
;
Alan R,Shuldiner [16]
;
Devin M,Absher [31]
;
Steve,Horvath [32]
;
Philip S,Tsao [33]
;
Sharon,Kardia [23]
;
Bruce M,Psaty [34]
;
Nona,Sotoodehnia [35]
;
Jordana T,Bell [29]
;
Erik,Ingelsson [36]
;
Wei,Chen [11]
;
Abbas,Dehghan [37]
;
Donna K,Arnett [9]
;
Melanie,Waldenberger [3]
;
Lifang,Hou [38]
;
Eric A,Whitsel [39]
;
Andrea,Baccarelli [40]
;
Daniel,Levy [41]
;
Myriam,Fornage [7]
;
Marguerite R,Irvin [9]
;
Themistocles L,Assimes [42]
作者单位:
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA. mina.jhun82@gmail.com.;Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. mina.jhun82@gmail.com.
[1]
Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.;Department of Cardiology, Boston Children's Hospital, Boston, MA, USA.
[2]
Research Unit Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.;Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.
[3]
Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.
[4]
Hebrew SeniorLife, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
[5]
Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
[6]
The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
[7]
Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
[8]
Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
[9]
Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
[10]
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
[11]
Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK.;GENYO, Center for Genomics and Oncological Research Pfizer/University of Granada/Andalusian Regional Government, Granada, Spain.
[12]
Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA.
[13]
Cardiovascular Health Research Unit, Departments of Medicine and Biostatistics, University of Washington, Seattle, WA, USA.
[14]
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
[15]
Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.;Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
[16]
Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
[17]
School of Public Health, University of Texas Health Science Center at Houston, Huston, TX, USA.
[18]
Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
[19]
Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.;IBE, Faculty of Medicine, LMU Munich, Munich, Germany.;Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany.
[20]
Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany.;Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.;Institute of Human Genetics, Technical University Munich, Munich, Germany.
[21]
Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.;Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany.
[22]
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.
[23]
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.;Survey Research Center, Institute for Social Research, Ann Arbor, MI, USA.
[24]
Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA.
[25]
Department of Internal Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
[26]
School of Biomedical Informatics, University of Texas Health Science Center at Houston, Houston, TX, USA.
[27]
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.;Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China.
[28]
Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK.
[29]
Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute, and Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.
[30]
HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
[31]
Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.;Department of Biostatistics, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA.
[32]
Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.;VA Palo Alto Healthcare System, Palo Alto, CA, USA.;Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA.
[33]
Cardiovascular Health Research Unit, Departments of Epidemiology, Medicine, and Health Services, University of Washington, Seattle, WA, USA.;Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
[34]
Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, WA, USA.
[35]
Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.;Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.;Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA.;Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA.
[36]
Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.;Department of Biostatistics and Epidemiology, MRC Centre for Environment and Health, School of Public Health, Imperial College, London, UK.
[37]
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
[38]
Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.;Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.
[39]
Department of Environmental Health Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.;Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY, USA.
[40]
Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.;Framingham Heart Study, Framingham, MA, USA.
[41]
Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. tassimes@stanford.edu.;VA Palo Alto Healthcare System, Palo Alto, CA, USA. tassimes@stanford.edu.;Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA. tassimes@stanford.edu.
[42]
主题词
成年人(Adult);老年人(Aged);肉碱O-软脂酰转移酶(Carnitine O-Palmitoyltransferase);CpG岛(CpG Islands);DNA甲基化(DNA Methylation);后成说, 遗传(Epigenesis, Genetic);表观基因组学(Epigenomics);女(雌)性(Female);人类(Humans);白细胞(Leukocytes);脂类(Lipids);脂蛋白类, HDL(Lipoproteins, HDL);男(雄)性(Male);中年人(Middle Aged);数量性状基因座位(Quantitative Trait Loci)
DOI
10.1038/s41467-021-23899-y
PMID
34183656
发布时间
2024-09-06
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