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Multivariate transcriptome analysis identifies networks and key drivers of chronic lymphocytic leukemia relapse risk and patient survival.

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第一作者： Ti'ara L,Griffen

第一单位： Department of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, 720 Westview Dr SW, HG 341B, Atlanta, GA, 30310, USA.

作者： Ti'ara L,Griffen ^[1] ; Eric B,Dammer ^[2] ; Courtney D,Dill ^[1] ; Kaylin M,Carey ^[1] ; Corey D,Young ^[1] ; Sha'Kayla K,Nunez ^[1] ; Adaugo Q,Ohandjo ^[1] ; Steven M,Kornblau ^[3] ; James W,Lillard ^[4]

作者单位： Department of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, 720 Westview Dr SW, HG 341B, Atlanta, GA, 30310, USA. ^[1] Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, 30322, USA. ^[2] Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. ^[3] Department of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, 720 Westview Dr SW, HG 341B, Atlanta, GA, 30310, USA. jlillard@msm.edu. ^[4]

关键词 ARHGAP27P2 C1S CASC2 CLEC3B CLL CRY1 CXCR5 FUT5 MID1IP1 Networks Relapse Survival URAHP WGCNA

医学主题词人类(Humans);白血病, 淋巴细胞, 慢性, B细胞(Leukemia, Lymphocytic, Chronic, B-Cell);基因表达谱(Gene Expression Profiling);基因调控网络(Gene Regulatory Networks);男(雄)性(Male);女(雌)性(Female);复发(Recurrence);多元分析(Multivariate Analysis);中年人(Middle Aged);老年人(Aged);肿瘤复发, 局部(Neoplasm Recurrence, Local);预后(Prognosis)

DOI 10.1186/s12920-021-01012-y

PMID 34187466

发布时间 2024-07-25

基金项目

R25 GM058268/GM/NIGMS NIH HHS/United States R25GM058268/GM/NIGMS NIH HHS/United States R25CA056452/CA/NCI NIH HHS/United States U54CA118638/CA/NCI NIH HHS/United States

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