Chemistry, Pharmacology and Therapeutic Potential of Swertiamarin - A Promising Natural Lead for New Drug Discovery and Development.

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作者： Nur Sakinah,Muhamad Fadzil ^[1] ; Mahendran,Sekar ^[1] ; Siew Hua,Gan ^[2] ; Srinivasa Reddy,Bonam ^[3] ; Yuan Seng,Wu ^[4] ; Jaishree,Vaijanathappa ^[5] ; Subban,Ravi ^[6] ; Pei Teng,Lum ^[1] ; Shivsharan B,Dhadde ^[7]

作者单位： Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of Medicine Perak, Ipoh, Perak, Malaysia. ^[1] School of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia. ^[2] Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Equipe-Immunopathologie et Immunointervention Thérapeutique, Sorbonne Université, Université de Paris, Paris, France. ^[3] Department of Biochemistry, School of Medicine, Faculty of Medicine, Bioscience and Nursing, MAHSA University, Bandar Saujana Putra, Selangor, Malaysia. ^[4] Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Mysuru, Karnataka, India. ^[5] Department of Chemistry, Karpagam Academy of Higher Education, Coimbatore, Tamil Nadu, India. ^[6] D.S.T.S. Mandal's College of Pharmacy, Solapur, Maharashtra, India. ^[7]

关键词 Enicostemma littorale biosynthesis inflammatory cytokines metabolic pathway molecular targets swertiamarin

主题词动物(Animals);药物发现(Drug Discovery);龙胆科(Gentianaceae);人类(Humans);环烯醚萜葡糖苷类(Iridoid Glucosides);植物提取物(Plant Extracts);吡喃酮类(Pyrones)

DOI 10.2147/DDDT.S299753

PMID 34188450

发布时间 2021-12-14

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