Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in Parkinson's disease.

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第一作者： Christopher E J,Doppler

第一单位： Institute of Neuroscience and Medicine (INM-3), Forschungszentrum Jülich, D-52425 Jülich, Germany.

作者： Christopher E J,Doppler ^[1] ; Martin B,Kinnerup ^[2] ; Corinna,Brune ^[3] ; Ezequiel,Farrher ^[2] ; Matthew,Betts ^[4] ; Tatyana D,Fedorova ^[5] ; Jeppe L,Schaldemose ^[6] ; Karoline,Knudsen ^[7] ; Rola,Ismail ^[3] ; Aline D,Seger ^[3] ; Allan K,Hansen ^[3] ; Kristian,Stær ^[3] ; Gereon R,Fink ^[1] ; David J,Brooks ^[2] ; Adjmal,Nahimi ^[3] ; Per,Borghammer ^[3] ; Michael,Sommerauer ^[1]

作者单位： Institute of Neuroscience and Medicine (INM-3), Forschungszentrum Jülich, D-52425 Jülich, Germany. ^[1] Faculty of Medicine and University Hospital Cologne, Department of Neurology, University of Cologne, D-50937 Köln, Germany. ^[2] Department of Nuclear Medicine and PET, Aarhus University Hospital, DK-8200 Aarhus N, Denmark. ^[3] Institute of Neuroscience and Medicine (INM-4), Forschungszentrum Jülich, D-52425 Jülich, Germany. ^[4] German Center for Neurodegenerative Diseases (DZNE), D-39120 Magdeburg, Germany. ^[5] Institute of Cognitive Neurology and Dementia Research, Otto-von-Guericke-University Magdeburg, D-39120 Magdeburg, Germany. ^[6] Center for Behavioral Brain Sciences, University of Magdeburg, D-39120 Magdeburg, Germany. ^[7] Division of Brain Sciences, Imperial College London, London SW7 2AZ, UK. ^[8] Institute of Translational and Clinical Research, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 7RU, UK. ^[9]

关键词 MeNER Parkinson’s disease neuromelanin noradrenaline positron emission tomography