The genetic association of the transcription factor NPAT with glycemic response to metformin involves regulation of fuel selection.
第一作者:
Changwei,Chen
第一单位:
Division of Cellular Medicine, School of Medicine, University of Dundee, Ninewells Hospital and Medical School, James Arnott Drive, Dundee, United Kingdom.
作者:
医学主题词
动物(Animals);血糖(Blood Glucose);细胞周期蛋白质类(Cell Cycle Proteins);细胞系, 肿瘤(Cell Line, Tumor);糖尿病, 2型(Diabetes Mellitus, Type 2);全基因组关联研究(Genome-Wide Association Study);血糖指数(Glycemic Index);HEK293细胞(HEK293 Cells);Hep G2细胞(Hep G2 Cells);人类(Humans);降血糖药(Hypoglycemic Agents);二甲双胍(Metformin);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);多态性, 单核苷酸(Polymorphism, Single Nucleotide)
DOI
10.1371/journal.pone.0253533
PMID
34197485
发布时间
2025-05-30
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PloS one
e0253533页
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