Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease.
作者:
主题词
腺苷一磷酸(Adenosine Monophosphate);丙氨酸(Alanine);苯胺化合物(Aniline Compounds);动物(Animals);抗病毒药(Antiviral Agents);苯甲酰胺类(Benzamides);药物评价, 临床前(Drug Evaluation, Preclinical);药物协同作用(Drug Synergism);酶测定(Enzyme Assays);黄素类(Flavins);荧光共振能量转移(Fluorescence Resonance Energy Transfer);呋喃类(Furans);高通量筛选分析(High-Throughput Screening Assays);半数抑制浓度(Inhibitory Concentration 50);萘类(Naphthalenes);菲类(Phenanthrenes);醌类(Quinones);结果可重复性(Reproducibility of Results);小分子化合物库(Small Molecule Libraries);Vero细胞(Vero Cells);病毒复制(Virus Replication)
DOI
10.1042/BCJ20210244
PMID
34198325
发布时间
2024-09-24
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The Biochemical journal
2517-2531页
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