首页> Cancers> HLA-G and HLA-E Immune Checkpoints Are Widely Expressed in Ewing Sarcoma but Have Limited Functional Impact on the Effector Functions of Antigen-Specific CAR T Cells.

HLA-G and HLA-E Immune Checkpoints Are Widely Expressed in Ewing Sarcoma but Have Limited Functional Impact on the Effector Functions of Antigen-Specific CAR T Cells.

导出 OA

翻译打印收藏纠错

第一作者： Bianca,Altvater

第一单位： Department of Pediatric Hematology and Oncology, University Children's Hospital Muenster, 48149 Muenster, Germany.

作者： Bianca,Altvater ^[1] ; Sareetha,Kailayangiri ^[1] ; Lina F,Pérez Lanuza ^[1] ; Katja,Urban ^[1] ; Lea,Greune ^[1] ; Maike,Flügge ^[1] ; Jutta,Meltzer ^[1] ; Nicole,Farwick ^[1] ; Simone,König ^[2] ; Dennis,Görlich ^[3] ; Wolfgang,Hartmann ^[4] ; Claudia,Rossig ^[5]

作者单位： Department of Pediatric Hematology and Oncology, University Children's Hospital Muenster, 48149 Muenster, Germany. ^[1] Core Unit Proteomics, Interdisciplinary Center for Clinical Research, 48149 Muenster, Germany. ^[2] Institute of Biostatistics and Clinical Research, University of Muenster, 48149 Muenster, Germany. ^[3] Gerhard-Domagk-Institute of Pathology, University of Muenster, 48149 Muenster, Germany. ^[4] Department of Pediatric Hematology and Oncology, University Children's Hospital Muenster, 48149 Muenster, Germany.;Cells-in-Motion Cluster of Excellence (EXC 1003-CiM), University of Muenster, 48149 Muenster, Germany. ^[5]

关键词 Ewing sarcoma HLA-E HLA-G cellular immunotherapy checkpoint inhibitors

DOI 10.3390/cancers13122857

PMID 34201079

发布时间 2021-07-05

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交