Genetic Analysis Reveals Differences in CD8<sup>+</sup> T Cell Epitope Regions That May Impact Cross-Reactivity of Vaccine-Induced T Cells against Wild-Type Mumps Viruses.

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第一作者： Patricia,Kaaijk

第一单位： Centre for Infectious Disease Control, National Institute for Public Health and the Environment, 3721 MA Bilthoven, The Netherlands.

作者： Patricia,Kaaijk ^[1] ; Maarten E,Emmelot ^[1] ; Jeroen,Kerkhof ^[1] ; Cécile A C M,van Els ^[2] ; Hugo D,Meiring ^[3] ; Jelle,de Wit ^[1] ; Rogier,Bodewes ^[1]

作者单位： Centre for Infectious Disease Control, National Institute for Public Health and the Environment, 3721 MA Bilthoven, The Netherlands. ^[1] Centre for Infectious Disease Control, National Institute for Public Health and the Environment, 3721 MA Bilthoven, The Netherlands.;Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands. ^[2] Intravacc (Institute for Translational Vaccinology), 3721 MA Bilthoven, The Netherlands. ^[3]

关键词 HLA-I Jeryl–Lynn mumps vaccine T cell cross-reactivity T cell epitopes T cell response antigenic variation cytotoxic CD8+ T cells immunoinformatics mumps virus wild-type strains

DOI 10.3390/vaccines9070699

PMID 34202193

发布时间 2021-07-28

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2021年9卷7期

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Genetic Analysis Reveals Differences in CD8<sup>+</sup> T Cell Epitope Regions That May Impact Cross-Reactivity of Vaccine-Induced T Cells against Wild-Type Mumps Viruses.

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Genetic Analysis Reveals Differences in CD8<sup>+</sup> T Cell Epitope Regions That May Impact Cross-Reactivity of Vaccine-Induced T Cells against Wild-Type Mumps Viruses.

Vaccines

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Vaccines

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