From Sampling to Sequencing: A Liquid Biopsy Pre-Analytic Workflow to Maximize Multi-Layer Genomic Information from a Single Tube.

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作者： Kendra K,Maass ^[1] ; Paulina S,Schad ^[2] ; Agnes M E,Finster ^[1] ; Pitithat,Puranachot ^[1] ; Fabian,Rosing ^[3] ; Tatjana,Wedig ^[4] ; Nathalie,Schwarz ^[1] ; Natalie,Stumpf ^[2] ; Stefan M,Pfister ^[1] ; Kristian W,Pajtler ^[2]

作者单位： German Cancer Research Center (DKFZ), Division of Pediatric Neurooncology, Hopp-Children's Cancer Center Heidelberg (KiTZ) and German Cancer Consortium (DKTK), 69120 Heidelberg, Germany. ^[1] Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, 69120 Heidelberg, Germany. ^[2] Division of Applied Bioinformatics, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. ^[3] Faculty of Medicine and Public Health, HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy, Bangkok 10210, Thailand. ^[4]

关键词 CSF blood preservation tubes cancer cell-free DNA cell-free RNA droplet digital PCR liquid biopsy low-coverage whole-genome sequencing pre-analytics size selection

DOI 10.3390/cancers13123002

PMID 34203921

发布时间 2021-07-05

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准确一般字义偏差语意偏离译文作用小提交