NOTCH signaling: Journey of an evolutionarily conserved pathway in driving tumor progression and its modulation as a therapeutic target.

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第一作者： Vaishali,Aggarwal

第一单位： Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, USA. Electronic address: vaishali.pgi@gmail.com.

作者： Vaishali,Aggarwal ^[1] ; Hardeep Singh,Tuli ^[2] ; Mehmet,Varol ^[3] ; Muobarak,Tuorkey ^[4] ; Katrin,Sak ^[5] ; Nidarshana Chaturvedi,Parashar ^[6] ; Tushar Singh,Barwal ^[7] ; Uttam,Sharma ^[8] ; Ashif,Iqubal ^[9] ; Gaurav,Parashar ^[10] ; Aklank,Jain ^[11]

作者单位： Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, USA. Electronic address: vaishali.pgi@gmail.com. ^[1] Department of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, 133 207, Haryana, India. Electronic address: hardeep.biotech@gmail.com. ^[2] Department of Molecular Biology and Genetics, Faculty of Science, Mugla Sitki Kocman University, Mugla, TR48000, Turkey. Electronic address: mehmetvarol@mu.edu.tr. ^[3] Division of Physiology, Zoology Department, Faculty of Science, Damanhour University, Damanhour, Egypt. Electronic address: mjtuorkey@sci.dmu.edu.eg. ^[4] NGO Praeventio, Tartu, 50407, Estonia. Electronic address: katrin.sak.001@mail.ee. ^[5] Department of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, 133 207, Haryana, India. Electronic address: nidarshanachaturvedi@gmail.com. ^[6] Department of Zoology, Central University of Punjab, Village-Ghudda, 151 401, Punjab, India. Electronic address: tushar101singhbarwal@gmail.com. ^[7] Department of Zoology, Central University of Punjab, Village-Ghudda, 151 401, Punjab, India. Electronic address: uttamsharma1994@gmail.com. ^[8] Department of Pharmacology, School of Pharmaceutical Education and Research (Formerly Faculty of Pharmacy), Jamia Hamdard (Deemed to be University), Delhi, India. Electronic address: asifiqubal2013@gmail.com. ^[9] Department of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, 133 207, Haryana, India. Electronic address: parashar22@gmail.com. ^[10] Department of Zoology, Central University of Punjab, Village-Ghudda, 151 401, Punjab, India. Electronic address: aklankjain@gmail.com. ^[11]

关键词 Cancer Hallmarks NOTCH Therapeutic targets

主题词生物学现象(Biological Phenomena);人类(Humans);肿瘤(Neoplasms);癌基因(Oncogenes);受体, Notch(Receptors, Notch);信号传导(Signal Transduction)

DOI 10.1016/j.critrevonc.2021.103403

PMID 34214610

发布时间 2021-08-10

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Critical reviews in oncology/hematology

2021年164卷

103403页

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NOTCH signaling: Journey of an evolutionarily conserved pathway in driving tumor progression and its modulation as a therapeutic target.

Critical reviews in oncology/hematology

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NOTCH signaling: Journey of an evolutionarily conserved pathway in driving tumor progression and its modulation as a therapeutic target.

Critical reviews in oncology/hematology

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Critical reviews in oncology/hematology

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