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首页> Chemico-biological interactions> Luteolin prevents THP-1 macrophage pyroptosis by suppressing ROS production via Nrf2 activation.

Luteolin prevents THP-1 macrophage pyroptosis by suppressing ROS production via Nrf2 activation.

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作者： Yongpeng,Zou ^[1] ; Xing,Luo ^[1] ; Yi,Feng ^[2] ; Shaohong,Fang ^[2] ; Jiangtian,Tian ^[2] ; Bo,Yu ^[3] ; Ji,Li ^[4]

作者单位： Department of Cardiology, 2nd Affiliated Hospital of Harbin Medical University, Harbin 150001, PR China. ^[1] Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin 150001, PR China. ^[2] Department of Cardiology, 2nd Affiliated Hospital of Harbin Medical University, Harbin 150001, PR China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin 150001, PR China. ^[3] Department of Cardiology, 2nd Affiliated Hospital of Harbin Medical University, Harbin 150001, PR China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin 150001, PR China. Electronic address: office_liji@126.com. ^[4]

关键词 Luteolin NF-κB NLRP3 inflammasome Nrf2 Pyroptosis ROS

主题词细胞系(Cell Line);基因表达调控(Gene Expression Regulation);人类(Humans);炎性体(Inflammasomes);木犀草素(Luteolin);巨噬细胞(Macrophages);NF-E2相关因子2(NF-E2-Related Factor 2);NF-κB(NF-kappa B);活性氧(Reactive Oxygen Species)

DOI 10.1016/j.cbi.2021.109573

PMID 34217685

发布时间 2021-08-02

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