Combining Metagenomic Sequencing With Whole Exome Sequencing to Optimize Clinical Strategies in Neonates With a Suspected Central Nervous System Infection.

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第一作者： Mengmeng,Ge

第一单位： Department of Neonatology, Children's Hospital, Fudan University, Shanghai, China.

作者： Mengmeng,Ge ^[1] ; Mingyu,Gan ^[2] ; Kai,Yan ^[1] ; Feifan,Xiao ^[1] ; Lin,Yang ^[2] ; Bingbing,Wu ^[3] ; Mili,Xiao ^[1] ; Yin,Ba ^[1] ; Rong,Zhang ^[1] ; Jin,Wang ^[1] ; Guoqiang,Cheng ^[1] ; Laishuan,Wang ^[1] ; Yun,Cao ^[1] ; Wenhao,Zhou ^[1] ; Liyuan,Hu ^[2]

作者单位： Department of Neonatology, Children's Hospital, Fudan University, Shanghai, China. ^[1] Clinical Genetic Center, Children's Hospital of Fudan University, Shanghai, China. ^[2] Children's Hospital of Fudan University, Shanghai Key Laboratory of Birth Defects, The Translational Medicine Center of Children Development and Disease of Fudan University, Shanghai, China. ^[3]

关键词 NICU WES metagenomic sequencing neonates suspected central nervous system infection

主题词中枢神经系统感染(Central Nervous System Infections);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);婴儿, 新生(Infant, Newborn);宏基因组(Metagenome);宏基因组学(Metagenomics);敏感性与特异性(Sensitivity and Specificity)

DOI 10.3389/fcimb.2021.671109

PMID 34222042

发布时间 2022-12-07

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