Tetralone derivatives are MIF tautomerase inhibitors and attenuate macrophage activation and amplify the hypothermic response in endotoxemic mice.
第一作者:
János,Garai
第一单位:
Department of Pathophysiology, Institute for Translational Medicine, University of Pécs, Medical School, Pécs, Hungary.
作者:
主题词
动物(Animals);细胞, 培养的(Cells, Cultured);剂量效应关系, 药物(Dose-Response Relationship, Drug);低温, 人工(Hypothermia, Induced);脂多糖类(Lipopolysaccharides);巨噬细胞活化(Macrophage Activation);巨噬细胞游走抑制因子(Macrophage Migration-Inhibitory Factors);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);模型, 分子(Models, Molecular);分子结构(Molecular Structure);构效关系(Structure-Activity Relationship);四氢萘酮类(Tetralones)
DOI
10.1080/14756366.2021.1916010
PMID
34225560
发布时间
2024-08-12
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