Plant-microbe interactions implicated in the production of camptothecin - An anticancer biometabolite from Phyllosticta elongata MH458897 a novel endophytic strain isolated from medicinal plant of Western Ghats of India.

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作者： Madhankumar,Dhakshinamoorthy ^[1] ; Senthil Kumar,Ponnusamy ^[2] ; Udaya Prakash,Nyayiru Kannaian ^[3] ; Bhuvaneswari,Srinivasan ^[4] ; Sripriya Nannu,Shankar ^[5] ; Kannan,Kilavan Packiam ^[6]

作者单位： Endophytic Fungal Metabolite Research Laboratory, Bannari Amman Institute of Technology, Sathyamangalam, Erode District, Tamil Nadu, India. Electronic address: dhakshnamadhananj89@gmail.com. ^[1] Department of Chemical Engineering, Sri Sivasubramaniya Nadar College of Engineering, Kalavakkam, Chennai, 603 110, India. Electronic address: senthilkumarp@ssn.edu.in. ^[2] Department of Biotechnology, School of Life Sciences, Vels University, Pallavaram, Chennai, TamilNadu, India. Electronic address: nkudayaprakash@gmail.com. ^[3] Department of Botany, Bharathi Women's College, Chennai, TamilNadu, India. Electronic address: drsbhuvaneswari8@gmail.com. ^[4] Marina Labs Research and Development, NT Patel Road, Nerkundram, Chennai, TamilNadu, India. Electronic address: nsripriya.bt@gmail.com. ^[5] Endophytic Fungal Metabolite Research Laboratory, Bannari Amman Institute of Technology, Sathyamangalam, Erode District, Tamil Nadu, India. Electronic address: drkpkannan@gmail.com. ^[6]

关键词 Anti-cancer Camptothecin MTT cytotoxicity assay Optimization Phyllosticta elongata

主题词子囊菌纲(Ascomycota);喜树碱(Camptothecin);生态系统(Ecosystem);人类(Humans);印度(India);植物, 药用(Plants, Medicinal)

DOI 10.1016/j.envres.2021.111564

PMID 34228950

发布时间 2021-10-08

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