Protective effects of tetramethylpyrazine on dysfunction of the locus coeruleus in rats exposed to single prolonged stress by anti-ER stress mechanism.

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第一作者： Yun,Hou

第一单位： Department of Histology and Embryology, Binzhou Medical University, No. 346 Guanhai Road, Yantai, 264003, Shandong, China.

作者： Yun,Hou ^[1] ; Meifeng,Li ^[2] ; Yinchuan,Jin ^[3] ; Feibo,Xu ^[1] ; Shaohua,Liang ^[4] ; Chen,Xue ^[5] ; Kaili,Wang ^[5] ; Wei,Zhao ^[6]

作者单位： Department of Histology and Embryology, Binzhou Medical University, No. 346 Guanhai Road, Yantai, 264003, Shandong, China. ^[1] Department of Intensive Care Unit, Yantai Yuhuangding Hospital Qingdao University, Yantai, 264000, Shandong, China. ^[2] Department of Medical Psychology, Fourth Military Medical University, No. 169 West Changle Road, Xi'an, 710032, China. ^[3] Department of Anatomy, Binzhou Medical University, No. 346 Guanhai Road, Yantai, 264003, Shandong, China. ^[4] Clinical Medicine College, Binzhou Medical University, No. 346 Guanhai Road, Yantai, 264003, Shandong, China. ^[5] Department of Histology and Embryology, Binzhou Medical University, No. 346 Guanhai Road, Yantai, 264003, Shandong, China. zhaowei_cathy@163.com. ^[6]

关键词 Endoplasmic reticulum stress Locus coeruleus Post-traumatic stress disorder Single prolonged stress Tetramethylpyrazine

主题词动物(Animals);细胞凋亡(Apoptosis);蓝斑(Locus Coeruleus);吡嗪类(Pyrazines);大鼠(Rats);应激障碍, 创伤后(Stress Disorders, Post-Traumatic)

DOI 10.1007/s00213-021-05908-6

PMID 34231002

发布时间 2021-10-15

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