Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women.
作者:
Babatunde,Adedokun [1]
;
Zhaohui,Du [2]
;
Guimin,Gao [3]
;
Thomas U,Ahearn [4]
;
Kathryn L,Lunetta [5]
;
Gary,Zirpoli [6]
;
Jonine,Figueroa [7]
;
Esther M,John [8]
;
Leslie,Bernstein [9]
;
Wei,Zheng [10]
;
Jennifer J,Hu [11]
;
Regina G,Ziegler [4]
;
Sarah,Nyante [12]
;
Elisa V,Bandera [13]
;
Sue A,Ingles [2]
;
Michael F,Press [14]
;
Sandra L,Deming-Halverson [10]
;
Jorge L,Rodriguez-Gil [15]
;
Song,Yao [16]
;
Temidayo O,Ogundiran [17]
;
Oladosu,Ojengbede [18]
;
William,Blot [10]
;
Melissa A,Troester [19]
;
Katherine L,Nathanson [20]
;
Anselm,Hennis [21]
;
Barbara,Nemesure [22]
;
Stefan,Ambs [22]
;
Peter N,Fiorica [23]
;
Lara E,Sucheston-Campbell [3]
;
Jeannette T,Bensen [24]
;
Lawrence H,Kushi [19]
;
Gabriela,Torres-Mejia [25]
;
Donglei,Hu [26]
;
Laura,Fejerman [27]
;
Manjeet K,Bolla [27]
;
Joe,Dennis [28]
;
Alison M,Dunning [28]
;
Douglas F,Easton [29]
;
Kyriaki,Michailidou [28]
;
Paul D P,Pharoah [29]
;
Qin,Wang [30]
;
Dale P,Sandler [28]
;
Jack A,Taylor [29]
;
Katie M,O'Brien [28]
;
Cari M,Kitahara [31]
;
Adeyinka G,Falusi [31]
;
Chinedum,Babalola [31]
;
Joel,Yarney [32]
;
Baffour,Awuah [33]
;
Beatrice,Addai-Wiafe [34]
;
GBHS Study Team [35]
;
Stephen J,Chanock [36]
;
Andrew F,Olshan [37]
;
Christine B,Ambrosone [4]
;
David V,Conti [19]
;
Elad,Ziv [16]
;
Olufunmilayo I,Olopade [2]
;
Montserrat,Garcia-Closas [27]
;
Julie R,Palmer [1]
;
Christopher A,Haiman [4]
;
Dezheng,Huo [6]
作者单位:
Center for Clinical Cancer Genetics and Global Health, Department of Medicine, University of Chicago, Chicago, IL, USA.
[1]
Department of Preventative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
[2]
Department of Public Health Sciences, University of Chicago, Chicago, IL, USA.
[3]
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
[4]
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
[5]
Slone Epidemiology Center, Boston University, Boston, MA, USA.
[6]
Usher Institute and CRUK Edinburgh Centre, University of Edinburgh, Edinburgh, UK.
[7]
Departments of Epidemiology & Population Health and of Medicine (Oncology) and Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.
[8]
Biomarkers of Early Detection and Prevention, Department of Population Sciences, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
[9]
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA.
[10]
Department of Public Health Sciences, University of Miami, Miami, FL, USA.
[11]
Department of Radiology, University of North Carolina, Chapel Hill, NC, USA.
[12]
Cancer Prevention and Control Program, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
[13]
Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
[14]
Genomics, Development and Disease Section, Genetic Disease Research Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA.
[15]
Department of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
[16]
Department of Surgery, College of Medicine, University of Ibadan, Ibadan, Nigeria.
[17]
Center for Population and Reproductive Health, College of Medicine, University of Ibadan, Ibadan, Nigeria.
[18]
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
[19]
Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
[20]
University of the West Indies, Bridgetown, Barbados.
[21]
Department of Family, Population and Preventive Medicine, Stony Brook University, Stony Brook, NY, USA.
[22]
Laboratory of Human Carcinogenesis, National Cancer Institute, Bethesda, MD, USA.
[23]
Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA.
[24]
Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
[25]
Center for Population Health Research, Instituto Nacional de Salud Publica, Cuernavaca, Mexico.
[26]
Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
[27]
Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
[28]
Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
[29]
Biostatistics Unit, The Cyprus Institute of Neurology & Genetics, Nicosia, Cyprus.
[30]
Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, USA.
[31]
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
[32]
Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Oyo, Nigeria.
[33]
Department of Pharmaceutical Chemistry, University of Ibadan, Ibadan, Oyo, Nigeria.
[34]
Korle Bu Teaching Hospital, Accra, Ghana.
[35]
Komfo Anokye Teaching Hospital, Kumasi, Ghana.
[36]
Peace and Love Hospital, Kumasi, Ghana.
[37]
Department of Preventative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. haiman@usc.edu.
[38]
Center for Clinical Cancer Genetics and Global Health, Department of Medicine, University of Chicago, Chicago, IL, USA. dhuo@health.bsd.uchicago.edu.
[39]
Department of Public Health Sciences, University of Chicago, Chicago, IL, USA. dhuo@health.bsd.uchicago.edu.
[40]
主题词
乳腺肿瘤(Breast Neoplasms);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);人类(Humans);内含子(Introns);多态性, 单核苷酸(Polymorphism, Single Nucleotide);数量性状基因座位(Quantitative Trait Loci)
DOI
10.1038/s41467-021-24327-x
PMID
34234117
发布时间
2024-02-10
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Nature communications
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