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NUDT15 polymorphism influences the metabolism and therapeutic effects of acyclovir and ganciclovir.

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第一作者： Rina,Nishii

第一单位： Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.

作者： Rina,Nishii ^[1] ; Takanori,Mizuno ^[2] ; Daniel,Rehling ^[3] ; Colton,Smith ^[1] ; Brandi L,Clark ^[4] ; Xujie,Zhao ^[1] ; Scott A,Brown ^[4] ; Brandon,Smart ^[1] ; Takaya,Moriyama ^[1] ; Yuji,Yamada ^[2] ; Tatsuo,Ichinohe ^[5] ; Makoto,Onizuka ^[6] ; Yoshiko,Atsuta ^[7] ; Lei,Yang ^[8] ; Wenjian,Yang ^[1] ; Paul G,Thomas ^[4] ; Pål,Stenmark ^[9] ; Motohiro,Kato ^[10] ; Jun J,Yang ^[11]

作者单位： Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA. ^[1] Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan. ^[2] Department of Biochemistry and Biophysics, Arrhenius Laboratories for Natural Sciences, Stockholm University, Stockholm, Sweden. ^[3] Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA. ^[4] Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan. ^[5] Tokai University School of Medicine, Kanagawa, Japan. ^[6] Japanese Data Center for Hematopoietic Cell Transplantation, Aichi, Japan. ^[7] Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA. ^[8] Department of Biochemistry and Biophysics, Arrhenius Laboratories for Natural Sciences, Stockholm University, Stockholm, Sweden. stenmark@dbb.su.se.;Department of Experimental Medical Science, Lund University, Lund, Sweden. stenmark@dbb.su.se. ^[9] Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan. katom-tky@umin.ac.jp. ^[10] Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA. jun.yang@stjude.org.;Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA. jun.yang@stjude.org.;Hematological Malignancies Program, Comprehensive Cancer Center, St. Jude Children's Research Hospital, Memphis, TN, USA. jun.yang@stjude.org. ^[11]