Pooled sputum to optimise the efficiency and utility of rapid, point-of-care molecular SARS-CoV-2 testing.

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作者： Alison,Burdett ^[1] ; Christofer,Toumazou ^[2] ; Rashmita,Sahoo ^[3] ; Adam,Mujan ^[2] ; Tsz-Kin,Hon ^[2] ; Judith,Bedzo-Nutakor ^[2] ; Nicola,Casali ^[2] ; Maria,Karvela ^[2] ; Mohammadreza,Sohbati ^[2] ; Graham S,Cooke ^[2] ; Gary W,Davies ^[4] ; Luke S P,Moore ^[5]

作者单位： DnaNudge Ltd, Imperial College White City Campus, The Translation and Innovation Hub, Level 11, 84 Wood Lane, London, W12 0BZ, UK. alison.burdett@dnanudge.com. ^[1] DnaNudge Ltd, Imperial College White City Campus, The Translation and Innovation Hub, Level 11, 84 Wood Lane, London, W12 0BZ, UK. ^[2] Department of Electrical and Electronic Engineering, Imperial College London, Exhibition Road, London, SW7 2AZ, UK. ^[3] North West London Pathology, Imperial College Healthcare NHS Trust, Fulham Palace Road, London, W6 8RF, UK. ^[4] NIHR Health Protection Research Unit in Healthcare Associated Infections & Antimicrobial Resistance, Imperial College London, Du Cane Road, London, W12 0NN, UK. ^[5] Chelsea and Westminster NHS Foundation Trust, 369 Fulham Road, London, SW10 9NH, UK. ^[6] North West London Pathology, Imperial College Healthcare NHS Trust, Fulham Palace Road, London, W6 8RF, UK. luke.moore@nhs.net. ^[7] NIHR Health Protection Research Unit in Healthcare Associated Infections & Antimicrobial Resistance, Imperial College London, Du Cane Road, London, W12 0NN, UK. luke.moore@nhs.net. ^[8] Chelsea and Westminster NHS Foundation Trust, 369 Fulham Road, London, SW10 9NH, UK. luke.moore@nhs.net. ^[9]

关键词 COVID-19 Coronavirus Molecular diagnostics PCR

主题词诊断试验, 常规(Diagnostic Tests, Routine);人类(Humans);检测限(Limit of Detection);鼻咽(Nasopharynx);敏感性与特异性(Sensitivity and Specificity);痰(Sputum);病毒载量(Viral Load)

DOI 10.1186/s12879-021-06316-z

PMID 34238234

发布时间 2021-07-13

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