miR-19a-3p downregulates tissue factor and functions as a potential therapeutic target for sepsis-induced disseminated intravascular coagulation.

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第一作者： Rong,Zhang

第一单位： Department of Pediatrics, Sichuan Academy of Medical Sciences&Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, No.32, West section2, 1st ring road, Qingyang District, Chengdu, Sichuan 610072, China.

作者： Rong,Zhang ^[1] ; Sifen,Lu ^[2] ; Xudan,Yang ^[3] ; Maojun,Li ^[1] ; Hui,Jia ^[1] ; Jing,Liao ^[1] ; Qing,Jing ^[1] ; Yanmei,Wu ^[1] ; Haichuan,Wang ^[1] ; Feng,Xiao ^[1] ; Xiaohong,Bai ^[1] ; Xiaoxue,Na ^[4] ; Yulin,Kang ^[5] ; Ling,Wan ^[6] ; Jiyun,Yang ^[7]

作者单位： Department of Pediatrics, Sichuan Academy of Medical Sciences&Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, No.32, West section2, 1st ring road, Qingyang District, Chengdu, Sichuan 610072, China. ^[1] Precision Medicine Key Laboratory of Sichuan Province and Precision Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China. ^[2] Department of Pathology, Sichuan Academy of Medical Sciences＆Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, No.32, West section2, 1st ring road, Qingyang District, Chengdu, Sichuan 610072, China. ^[3] School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China. ^[4] Institute of Environmental Information, Chinese Research Academy of Environmental Sciences, Beijing 100012, China. Electronic address: ylkang@pku.edu.cn. ^[5] Department of Ophthalmology, Sichuan Academy of Medical Sciences＆Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, No.32, West section2, 1st ring road, Qingyang District, Chengdu, Sichuan 610072, China. Electronic address: wanling@med.uestc.edu.cn. ^[6] The Key Laboratory for Human Disease Gene Study of Sichuan Province, Prenatal Diagnosis Center, Sichuan Academy of Medical Sciences＆Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, No.32, West section2, 1st ring road, Qingyang District, Chengdu, Sichuan 610072, China. Electronic address: yangjiyun@med.uestc.edu.cn. ^[7]

关键词 Biomarker Coagulation cascade Disseminated intravascular coagulation Therapeutic target Tissue factor miR-19a-3p