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A mouse model of lethal respiratory dysfunction for SARS-CoV-2 infection.

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第一作者： Esther S,Gan

第一单位： Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore. Electronic address: esther.gan@duke-nus.edu.sg.

作者： Esther S,Gan ^[1] ; Ayesa,Syenina ^[2] ; Martin,Linster ^[3] ; Benson,Ng ^[4] ; Summer L,Zhang ^[3] ; Satoru,Watanabe ^[3] ; Ravisankar,Rajarethinam ^[5] ; Hwee Cheng,Tan ^[3] ; Gavin Jd,Smith ^[3] ; Eng Eong,Ooi ^[6]

作者单位： Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore. Electronic address: esther.gan@duke-nus.edu.sg. ^[1] Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore; Viral Research and Experimental Medicine Centre, SingHealth Duke-NUS Academic Medical Centre, 20 College Road, Singapore, 169856, Singapore. ^[2] Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore. ^[3] Office of Research Affairs, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore. ^[4] Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Singapore, 138673, Singapore. ^[5] Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore; Viral Research and Experimental Medicine Centre, SingHealth Duke-NUS Academic Medical Centre, 20 College Road, Singapore, 169856, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, #10-01, Singapore, 117549, Singapore. Electronic address: engeong.ooi@duke-nus.edu.sg. ^[6]

关键词 Genetic variants K18-hACE2 mice Pneumonia SARS-CoV-2